Needham & Company 2012 Biotech Preview

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Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) Delayed: 231.24 -2.05 (0.88%)
Previous Close $233.29    52 Week High $109.10 
Open $237.73    52 Week Low $31.38 
Day High $238.96    P/E N/A 
Day Low $230.01    EPS $-1.45 
Volume 734,807       

Cubist Pharmaceuticals, Inc. (NASDAQ: CBST) Delayed: 101.94 --0 (-0%)
Previous Close $101.94    52 Week High $101.99 
Open $3.23    52 Week Low $58.50 
Day High $101.94    P/E N/A 
Day Low $101.94    EPS $-0.27 
Volume 3,714       

Dendreon Corp (NASDAQ: DNDN) Delayed: 0.13 --0 (-0%)
Previous Close $0.13    52 Week High $3.46 
Open $11.75    52 Week Low $0.11 
Day High $0.13    P/E N/A 
Day Low $0.13    EPS $-1.63 
Volume 279       

Gilead Sciences (NASDAQ: GILD) Delayed: 155.36 +2.29 (1.50%)
Previous Close $153.07    52 Week High $108.63 
Open $155.37    52 Week Low $71.39 
Day High $157.48    P/E 85.83 
Day Low $154.02    EPS $1.81 
Volume 2,334,637       

Human Genome Sciences, Inc. (NASDAQ: HGSI) Delayed: 14.24 --0 (-0%)
Previous Close $14.24    52 Week High $16.58 
Open $55.80    52 Week Low $6.51 
Day High $14.24    P/E N/A 
Day Low $14.24    EPS $-1.79 
Volume 557,147       

Johnson & Johnson (NYSE: JNJ) Delayed: 259.41 +5.62 (2.21%)
Previous Close $253.79    52 Week High $126.07 
Open $257.48    52 Week Low $94.28 
Day High $260.77    P/E 53.93 
Day Low $256.42    EPS $4.81 
Volume 3,204,791       

Lexicon Pharmaceuticals, Inc. (NASDAQ: LXRX) Delayed: 1.61 +0.06 (3.87%)
Previous Close $1.55    52 Week High $19.62 
Open $1.56    52 Week Low $7.65 
Day High $1.63    P/E N/A 
Day Low $1.55    EPS $-0.22 
Volume 765,693       

Micromet, Inc. (AMEX: MITI) Delayed: 0.04 --0 (-0%)
Previous Close $0.04    52 Week High $11.00 
Open $0.04    52 Week Low $4.13 
Day High $0.04    P/E N/A 
Day Low $0.04    EPS $-0.81 
Volume 14,162       

Optimer Pharmaceuticals, Inc. (NASDAQ: OPTR) Delayed: 12.78 --0 (-0%)
Previous Close $12.78    52 Week High $16.80 
Open $12.78    52 Week Low $8.64 
Day High $12.78    P/E N/A 
Day Low $12.78    EPS $-1.75 
Volume 1,179,540       

Pharmacyclics, Inc. (NASDAQ: PCYC) Delayed: 261.25 --0 (-0%)
Previous Close $261.25    52 Week High $261.68 
Open $0.82    52 Week Low $85.50 
Day High $261.25    P/E 300.29 
Day Low $261.25    EPS $0.87 
Volume 3,226       

Seattle Genetics Inc /wa (NASDAQ: SGEN) Delayed: 228.74 --0 (-0%)
Previous Close $228.74    52 Week High $75.36 
Open $22.94    52 Week Low $26.02 
Day High $228.74    P/E N/A 
Day Low $228.74    EPS $-0.51 
Volume 759,302       

Targacept, Inc. (NASDAQ: TRGT) Delayed: 0.96 --0 (-0%)
Previous Close $0.96    52 Week High $3.23 
Open $0.01    52 Week Low $0.82 
Day High $0.96    P/E N/A 
Day Low $0.96    EPS $-1.39 
Volume 3,200       

Vertex Pharmaceuticals Inc (NASDAQ: VRTX) Delayed: 507.80 +5.85 (1.17%)
Previous Close $501.95    52 Week High $134.71 
Open $507.89    52 Week Low $73.31 
Day High $514.11    P/E N/A 
Day Low $505.00    EPS $-1.98 
Volume 441,408       

Pharmasset, Inc. (AMEX: VRUS) Delayed: 0.00 --0 (-0%)
Previous Close $0.00    52 Week High $137.81 
Open $67.86    52 Week Low $46.49 
Day High $0.00    P/E 0.00 
Day Low $0.00    EPS $-1.25 
Volume 34,954