NextCure and Avere to merge, targeting oral IL-23 therapy
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NextCure and Avere Therapeutics Announce Merger to Advance Once-Weekly Oral IL-23 Therapy
July 14, 2026 6:00 AM EDTAvere Therapeutics lead program, AVR-001, is a differentiated oral peptide interleukin-23 (IL-23) receptor antagonist, with Phase 1b psoriasis data supporting its potential to be rapidly developed as a convenient, once-weekly oral therapy
Concurrent $320 million private investment from world-class investor syndicate ensures combined company is well-capitalized to accelerate development of AVR-001
Companys financial runway expected to fund AVR-001 through Phase 2b readout in psoriasis, initiation of a Phase 3 trial in psoriasis, and initiation of a Phase 2b trial in ulcerative colitis
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