Bayer reports phase I results for prostate cancer therapy
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Bayer Reports Results for the Investigational Targeted Radionuclide Therapy ²²⁵Ac-PSMA-Trillium in Advanced Metastatic Prostate Cancer
February 27, 2026 12:43 PM ESTÂ 225Ac-PSMA-Trillium (BAY 3563254) is an investigational targeted alpha therapy (TAT) being developed for patients with advanced metastatic castration-resistant prostate cancer (mCRPC) Data from PAnTHa, the global Phase I first-in-human, dose-escalation study were presented during the 2026 American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco, CA Data support advancing 225Ac-PSMA-Trillium to the next phase of development Prostate cancer is the second most common diagnosed cancer in men1, with less than three years median survival among metastatic patients, who have developed castration-resistance2 TAT is a strategic pillar of precision oncology at... More
