BIOGEN publishes study results for high-dose nusinersen in Nature Medicine

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Go back to BIOGEN publishes study results for high-dose nusinersen in Nature Medicine

Nature Medicine Publishes Results from the Pivotal DEVOTE Study of High-Dose Regimen of Nusinersen in Spinal Muscular Atrophy

February 4, 2026 7:30 AM EST

Findings from DEVOTE support clinical benefits of the high-dose regimen of nusinersen (50 mg and 28 mg) in both treatment-naïve individuals and those previously treated with 12 mg nusinersenThe high-dose regimen of nusinersen also slowed neurodegeneration more rapidly, as measured by neurofilament, than the 12 mg regimen

CAMBRIDGE, Mass., Feb. 04, 2026 (GLOBE NEWSWIRE) --... More