Stoke Therapeutics and Biogen present zorevunersen data at epilepsy meeting

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Go back to Stoke Therapeutics and Biogen present zorevunersen data at epilepsy meeting

Stoke Therapeutics and Biogen Present Data that Further Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 2025 American

December 5, 2025 9:00 AM EST

Long-term Phase 1/2a and open label extension (OLE) data for zorevunersen on top of standard of care anti-seizure medicines (ASMs) demonstrate durable seizure reductions, including increases in seizure-free days, in addition to improvements in cognition, behavior and quality of life

Propensity score weighted analysis comparing the effects of zorevunersen to natural history showed reductions in seizures and improvements in cognition and behavior with dose levels and timepoints similar to and consistent with the ongoing Phase 3 EMPEROR study

Analysis of electroencephalogram (EEG) supports a disease-modifying mechanism of action

BEDFORD, Mass.... More