Longeveron presents MRI data on stem cell therapy for Alzheimer's

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Go back to Longeveron presents MRI data on stem cell therapy for Alzheimer's

Longeveron New MRI Biomarker Data Linking Neuroinflammation to Clinical Outcomes in Patients with Mild Alzheimer’s Disease Presented at the Clinical Trials on Alzheimer’s Disease Conference (CTAD

December 1, 2025 12:00 PM EST

Results obtained in the Phase 2 placebo-controlled CLEAR-MIND clinical trial showed that treatment with stem cell therapy laromestrocel was associated with a reduction in MRI measured neuroinflammation compared to placebo across multiple key brain regions, including key Alzheimers disease-associated regions, most notably in the hippocampusReduction in hippocampal neuroinflammation, measured using MRI assessed free water, correlated strongly with preservation of hippocampal volume and with clinical outcomesFindings suggest a sustained anti-inflammatory effect of laromestrocel, reinforcing its... More