Vertex Pharma (VRTX) Provides Updates on Multiple Kidney Programs

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Vertex Provides Updates on Multiple Kidney Programs at the American Society of Nephrology (ASN) Annual Kidney Week Congress

October 25, 2024 1:00 PM UTC

- New data on povetacicept 80 mg SC Q4 weeks in IgA nephropathy shows mean UPCR reduction from baseline of 66% observed at 48 weeks, associated with stable renal function (eGFR) and 63% achieving clinical remission --

- First proteinuria data on povetacicept in primary membranous nephropathy shows mean UPCR reduction from baseline of 62% at 24 weeks

- Global Phase 3 RAINIER trial of povetacicept in IgA nephropathy now underway

Enrollment and dosing ongoing in Phase 3 portion of the global Phase 2/3 pivotal... More