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Form SC 13G/A HEALTHSTREAM INC Filed by: FMR LLC

February 12, 2016 9:15 AM EST

SCHEDULE 13G Amendment No. 3 HEALTHSTREAM INC COMMON STOCK Cusip #42222N103 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [x] Rule 13d-1(b) [ ] Rule 13d-1(c) [ ] Rule 13d-1(d) Cusip #42222N103 Item 1: Reporting Person - FMR LLC Item 2: (a) [ ] (b) [ ] Item 4: Delaware Item 5: 133,500 Item 6: 0 Item 7: 4,746,889 Item 8: 0 Item 9: 4,746,889 Item 11: 14.999% Item 12: HC Cusip #42222N103 Item 1: Reporting Person - Abigail P. Johnson Item 2: (a) [ ] (b) [ ] Item 4: United States of America Item 5: 0 Item 6: 0 Item 7: 4,746,889 Item 8: 0 Item 9: 4,746,889 Item 11: 14.999% Item 12: IN Cusip #42222N103 Item 1: Reporting Person - Select Health Care Portfolio Item 2: (a) [ ] (b) [ ] Item 4: Massachusetts Item 5: 2,000,000 Item 6: 0 Item 7: 0 Item 8:... More