Routes Europe Opens Amidst Global Open Skies Debate
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Shire's (SHPG) Phase 2 IMAGO Missed Primary, Secondary Endpoints
April 9, 2015 6:09 AM EDTShire plc (NASDAQ: SHPG) announced that the 13-week Phase 2 IMAGO trial of its investigational compound SHP625 (LUM001) did not meet the primary or secondary endpoints in the study of 20 pediatric patients with Alagille syndrome (ALGS), a rare, life-threatening genetic disorder that presents with chronic cholestasis (accumulation of bile acids in the liver) and severe pruritus (itching). The primary endpoint was the... More

