Notable Holders of (XENE)
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Expand Research on XENE
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* Does Not Fully Represent All Holders
| Fund | Title | Shares | % Owned | Source |
|---|---|---|---|---|
| Fidelity Investments | COM | 5,188,707 | N/A | 13F |
| venBio Select Advisor LLC | Common | 4,900,000 | N/A | 13F |
| DRIEHAUS CAPITAL MANAGEMENT LLC | ADR | 4,760,853 | N/A | 13F |
| HENDERSON GROUP PLC | COM | 4,084,034 | N/A | 13F |
| Polar Capital Holdings Plc | COM | 3,003,747 | N/A | 13F |
| Capital Research & Management Co - Division 3 | COM | 2,321,991 | N/A | 13F |
| Marshall Wace LLP | COMMON STOCK | 2,320,419 | N/A | 13F |
| Capital World Investors | COM | 2,274,974 | N/A | 13F |
| PICTET ASSET MANAGEMENT SA | COM | 2,032,730 | N/A | 13F |
| LORD ABBETT & CO LLC | COM | 1,958,540 | N/A | 13F |
| BRAIDWELL LP | COM | 1,828,353 | N/A | 13F |
| COMMODORE CAPITAL LP | COM | 1,659,111 | N/A | 13F |
| ALLIANCEBERNSTEIN L.P. | COM | 1,593,814 | N/A | 13F |
| STATE STREET CORP | COM | 1,492,550 | N/A | 13F |
| PERCEPTIVE ADVISORS LLC | COM | 1,223,377 | N/A | 13F |
| Rock Springs Capital Management LP | COM | 1,178,002 | N/A | 13F |
| Redmile Group, LLC | COM | 1,120,476 | N/A | 13F |
| OrbiMed Advisors | COM | 1,096,000 | N/A | 13F |
| Paradigm Biocapital Advisors LP | COM | 989,327 | N/A | 13F |
| SAMLYN CAPITAL, LLC | COM | 939,909 | N/A | 13F |
| BVF INC/IL | COM | 901,095 | N/A | 13F |
| PRICE T ROWE ASSOCIATES INC /MD/ | COMM STK | 862,300 | N/A | 13F |
| Nicholas Investment Partners, LP | COM | 791,118 | N/A | 13F |
| FRANKLIN RESOURCES INC | COM | 758,059 | N/A | 13F |
| LOOMIS SAYLES & CO L P | COMMON | 753,526 | N/A | 13F |
| BAKER BROS ADVISORS LLC | COM | 751,639 | N/A | 13F |
| Holocene Advisors, LP | COM | 712,478 | N/A | 13F |
| Candriam Luxembourg S.C.A. | COM | 705,884 | N/A | 13F |
| Goldman Sachs Asset Management, L.P. | CMN | 696,047 | N/A | 13F |
| FEDERATED INVESTORS INC /PA/ | COM | 672,237 | N/A | 13F |
| Adage Capital | COM | 670,000 | N/A | 13F |
| BARCLAYS PLC | COM | 600,964 | N/A | 13F |
| Boxer Capital, LLC | COM | 600,000 | N/A | 13F |
| TimesSquare Capital Management, LLC | COM | 590,575 | N/A | 13F |
| FIERA SCEPTRE INC. | COM | 549,341 | N/A | 13F |
| GREAT POINT PARTNERS LLC | COM | 530,000 | N/A | 13F |
| Avidity Partners Management LP | COM | 481,300 | N/A | 13F |
| NORTHERN TRUST CORP | COM | 438,714 | N/A | 13F |
| EVENTIDE ASSET MANAGEMENT, LLC | COM | 413,906 | N/A | 13F |
| First Light Asset Management, LLC | Common Stocks | 338,646 | N/A | 13F |
| Woodline Partners LP | COM | 290,400 | N/A | 13F |
| DAFNA Capital Management LLC | COM | 280,538 | N/A | 13F |
| Logos Global Management LP | COM | 275,000 | N/A | 13F |
| Ally Bridge Group (NY) LLC | COM | 266,961 | N/A | 13F |
| DIMENSIONAL FUND ADVISORS LP | COM | 262,107 | N/A | 13F |
| VANGUARD GROUP INC | COM | 261,353 | N/A | 13F |
| GRANAHAN INVESTMENT MANAGEMENT INC/MA | COM | 236,753 | N/A | 13F |
| Altium Capital Management LP | COM | 228,000 | N/A | 13F |
| BANK OF AMERICA CORP /DE/ | COM | 221,368 | N/A | 13F |
| Parkman Healthcare Partners LLC | COM | 217,740 | N/A | 13F |
| MILLENNIUM MANAGEMENT LLC | COM | 213,338 | N/A | 13F |
| STATE OF WISCONSIN INVESTMENT BOARD | COM | 212,129 | N/A | 13F |
| JENNISON ASSOCIATES LLC | COM | 188,391 | N/A | 13F |
| Ghost Tree Capital, LLC | COM | 185,000 | N/A | 13F |
| NEW YORK STATE COMMON RETIREMENT FUND | Foreign Stock | 184,631 | N/A | 13F |
| Schonfeld Strategic Advisors LLC | COM | 180,143 | N/A | 13F |
| Eversept Partners, LLC | COM | 171,378 | N/A | 13F |
| PUTNAM INVESTMENTS LLC | ORDINARY SHARES | 165,262 | N/A | 13F |
| Ensign Peak Advisors, Inc | COM | 164,380 | N/A | 13F |
| WELLS FARGO & CO/MN | COM | 152,297 | N/A | 13F |
| Russell Investments Group, Ltd. | Common Stock | 150,456 | N/A | 13F |
| NOMURA HOLDINGS INC (CALL) | COM | 150,000 | N/A | 13F |
| ALGERT COLDIRON INVESTORS LLC | COM | 144,877 | N/A | 13F |
| KNOTT DAVID M | Common | 144,101 | N/A | 13F |
| UniSuper Management Pty Ltd | COM | 140,168 | N/A | 13F |
| Ikarian Capital, LLC | COM | 135,486 | N/A | 13F |
| Walleye Trading Advisors, LLC | COM | 126,028 | N/A | 13F |
| Nan Fung Group Holdings Ltd | COM | 114,380 | N/A | 13F |
| DnB NOR Asset Management AS | common | 112,629 | N/A | 13F |
| Swiss National Bank | COM | 109,800 | N/A | 13F |
| AMERIPRISE FINANCIAL INC | COM | 109,544 | N/A | 13F |
| Partner Fund Management, L.P. | COM | 100,147 | N/A | 13F |
| BAMCO INC /NY/ | COM | 100,100 | N/A | 13F |
| SILVERARC CAPITAL MANAGEMENT, LLC | EQUITIES | 99,756 | N/A | 13F |
| D. E. Shaw & Co., INC. | COM | 98,745 | N/A | 13F |
| ROYAL BANK OF CANADA \ | COM | 89,757 | N/A | 13F |
| RAYMOND JAMES FINANCIAL INC | COM | 83,255 | N/A | 13F |
| Moran Wealth Management, LLC | COM | 68,930 | N/A | 13F |
| Atika Capital Management LLC | COM | 68,050 | N/A | 13F |
| Hambrecht & Quist Capital Management LLC | Common | 67,506 | N/A | 13F |
| ING INVESTMENT MANAGEMENT LLC | COM | 67,140 | N/A | 13F |
| Soleus Capital Management, L.P. | COM | 66,000 | N/A | 13F |
| CREDIT SUISSE AG/ | COM | 65,827 | N/A | 13F |
| State of New Jersey Common Pension Fund D | COM | 64,454 | N/A | 13F |
| Affinity Asset Advisors, LLC | COM | 60,376 | N/A | 13F |
| JANE STREET GROUP, LLC (CALL) | COM | 57,900 | N/A | 13F |
| GEODE CAPITAL MANAGEMENT LLC | COM | 55,915 | N/A | 13F |
| UBS GLOBAL ASSET MANAGEMENT AMERICAS INC | NON US EQTY | 53,052 | N/A | 13F |
| UBS Group AG | COM | 52,539 | N/A | 13F |
| Invesco Ltd. | COM | 50,947 | N/A | 13F |
| J. Goldman & Co LP | COM | 48,041 | N/A | 13F |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | COMMON | 47,957 | N/A | 13F |
| ALPS ADVISORS INC | COM | 46,723 | N/A | 13F |
| Bank of New York Mellon CORP | COM | 46,597 | N/A | 13F |
| ADVISORY RESEARCH INC | COM | 44,422 | N/A | 13F |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | COMMON STOCK | 44,375 | N/A | 13F |
| SEI INVESTMENTS CO | COM | 43,858 | N/A | 13F |
| LEGAL & GENERAL GROUP PLC | COM | 42,792 | N/A | 13F |
| CIBC World Markets Inc. | COM | 41,222 | N/A | 13F |
| Nuveen Asset Management, LLC | COM | 40,199 | N/A | 13F |
| SG Americas Securities, LLC | COM | 39,262 | N/A | 13F |
| UBS OCONNOR LLC | COM | 38,676 | N/A | 13F |
| TLS Advisors LLC | COM | 32,956 | N/A | 13F |
| Qube Research & Technologies Ltd | COM | 29,967 | N/A | 13F |
| TWINBEECH CAPITAL LP | COM | 27,468 | N/A | 13F |
| PARAMETRIC PORTFOLIO ASSOCIATES | Common Stock | 26,338 | N/A | 13F |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC | COM | 25,500 | N/A | 13F |
| WOLVERINE TRADING, LLC (PUT) | COM | 25,300 | N/A | 13F |
| NJ State Employees Deferred Compensation Plan | COM | 25,000 | N/A | 13F |
| Tri Locum Partners LP | COM | 24,221 | N/A | 13F |
| Bellevue Group AG | COM | 23,900 | N/A | 13F |
| Knott David M Jr | Common | 23,866 | N/A | 13F |
| CHARTWELL INVESTMENT PARTNERS, INC. | cs | 23,301 | N/A | 13F |
| NATIXIS ASSET MANAGEMENT ADVISORS, L.P. | COM | 22,020 | N/A | 13F |
| SANDERS MORRIS HARRIS INC. | COM | 21,500 | N/A | 13F |
| DekaBank Deutsche Girozentrale | COM | 20,000 | N/A | 13F |
| TWO SIGMA INVESTMENTS LLC | COM | 18,633 | N/A | 13F |
| GROUP ONE TRADING, L.P. (CALL) | COM | 18,300 | N/A | 13F |
| HRT FINANCIAL LLC | COM | 17,946 | N/A | 13F |
| Calamos Advisors LLC | COM | 17,637 | N/A | 13F |
| HighVista Strategies LLC | COM | 17,575 | N/A | 13F |
| STIFEL FINANCIAL CORP | COM | 17,548 | N/A | 13F |
| OPPENHEIMER FUNDS INC | COM | 16,998 | N/A | 13F |
| ENVESTNET ASSET MANAGEMENT INC | COM | 16,522 | N/A | 13F |
| Orion Portfolio Solutions, LLC | COM | 15,806 | N/A | 13F |
| SPRINGBOK CAPITAL MANAGEMENT, LLC | COM | 15,472 | N/A | 13F |
| SHELL ASSET MANAGEMENT CO | COM | 14,515 | N/A | 13F |
| Arizona State Retirement System | COM | 14,165 | N/A | 13F |
| Handelsbanken Fonder AB | COM | 14,100 | N/A | 13F |
| TEACHER RETIREMENT SYSTEM OF TEXAS | COM | 13,672 | N/A | 13F |
| Allianz Asset Management AG | COM | 13,200 | N/A | 13F |
| Legato Capital Management LLC | COM | 12,310 | N/A | 13F |
| Supplemental Annuity Collective Trust of NJ | COM | 11,000 | N/A | 13F |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | COM | 10,633 | N/A | 13F |
| Marex Group plc | COM | 10,557 | N/A | 13F |
| GUGGENHEIM CAPITAL LLC | COM | 10,374 | N/A | 13F |
| Elmwood Wealth Management, Inc. | COM | 10,069 | N/A | 13F |
| Birchview Capital, LP | COM | 10,000 | N/A | 13F |
| BOOTHBAY FUND MANAGEMENT, LLC | COM | 9,983 | N/A | 13F |
| Belvedere Trading LLC (CALL) | COM | 9,800 | N/A | 13F |
| Zurcher Kantonalbank (Zurich Cantonalbank) | COM | 9,193 | N/A | 13F |
| Advisors Asset Management, Inc. | COM | 8,092 | N/A | 13F |
| Trexquant Investment LP | COM | 7,446 | N/A | 13F |
| CITIGROUP INC | COM | 7,361 | N/A | 13F |
| NATIXIS | COM | 7,000 | N/A | 13F |
| Walleye Trading LLC | COM | 6,923 | N/A | 13F |
| PNC FINANCIAL SERVICES GROUP INC | COM | 6,574 | N/A | 13F |
| VICTORY CAPITAL MANAGEMENT INC | COM | 6,500 | N/A | 13F |
| OPPENHEIMER ASSET MANAGEMENT INC | COM | 6,230 | N/A | 13F |
| Connacht Asset Management LP | COM | 6,165 | N/A | 13F |
| Snowden Capital Advisors LLC | COM | 5,996 | N/A | 13F |
| GENWORTH FINANCIAL WEALTH MANAGEMENT, INC | COM | 5,845 | N/A | 13F |
| Tower Research Capital LLC | COM | 5,524 | N/A | 13F |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | COM | 5,000 | N/A | 13F |
| CITIZENS FINANCIAL GROUP INC/RI | COM | 5,000 | N/A | 13F |
| MACKENZIE FINANCIAL CORP | COM | 4,772 | N/A | 13F |
| PRINCIPAL FINANCIAL GROUP INC | COM | 4,488 | N/A | 13F |
| EXCHANGE TRADED CONCEPTS, LLC | COM | 3,247 | N/A | 13F |
| KBC Group NV | COM | 2,780 | N/A | 13F |
| Virtus ETF Advisers LLC | COM | 2,552 | N/A | 13F |
| DEUTSCHE BANK AG\ | COM | 2,495 | N/A | 13F |
| IFP Advisors, Inc | cs | 2,178 | N/A | 13F |
| Cubist Systematic Strategies, LLC | COM | 1,955 | N/A | 13F |
| GREAT WEST LIFE ASSURANCE CO /CAN/ | COM | 1,693 | N/A | 13F |
| BNP PARIBAS ARBITRAGE, SA | Equity | 1,441 | N/A | 13F |
| China Universal Asset Management Co., Ltd. | Common Stock | 833 | N/A | 13F |
| Parallel Advisors, LLC | Stock | 776 | N/A | 13F |
| HARBOR CAPITAL ADVISORS, INC. | COM | 547 | N/A | 13F |
| FTB Advisors, Inc. | COMMON STOCK | 370 | N/A | 13F |
| Householder Group Estate & Retirement Specialist, LLC | Common Stock | 283 | N/A | 13F |
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ | Com | 235 | N/A | 13F |
| Daiwa Securities Group Inc. | COM | 229 | N/A | 13F |
| NATIONAL BANK OF CANADA /FI/ | COM | 190 | N/A | 13F |
| US BANCORP \DE\ | COM | 175 | N/A | 13F |
| JONES FINANCIAL COMPANIES LLLP | FOREIGN | 150 | N/A | 13F |
| Hexagon Capital Partners LLC | Stock | 82 | N/A | 13F |
| WHITTIER TRUST CO OF NEVADA INC | NON-US EQUITY (DEVELOPED) | 38 | N/A | 13F |
| Park Place Capital Corp | Common stock | 22 | N/A | 13F |
| SIGNATUREFD, LLC | COM | 13 | N/A | 13F |
| SJS Investment Consulting Inc. | COM | 2 | N/A | 13F |
| Disciplined Investments, LLC | Stock | 1 | N/A | 13F |
| AdvisorNet Financial, Inc | Stock | 1 | N/A | 13F |
| JFS WEALTH ADVISORS, LLC | COM | 1 | N/A | 13F |
| Lindbrook Capital, LLC | Stock | 0 | N/A | 13F |
| NOMURA ASSET MANAGEMENT CO LTD | COM | 0 | N/A | 13F |
