Notable Holders of Orexigen Therapeutics, Inc. (OREX)
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* Does Not Fully Represent All Holders
| Fund | Title | Shares | % Owned | Source |
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| GLG LLC | COM NEW | 1,524,143 | 1.31% | 13F |
| Timberline Asset Management LLC | Com | 623,462 | 0.54% | 13F |
| SPARK LP /DE | COM | 294,500 | 0.25% | 13F |
| BlackRock Institutional Trust Company, N.A. | COM NEW | 213,649 | 0.18% | 13F |
| SUTTONBROOK CAPITAL MANAGEMENT LP | COM | 200,000 | 0.17% | 13F |
| UBS AG | COM | 119,782 | 0.10% | 13F |
| MUNDER CAPITAL MANAGEMENT | COM | 89,557 | 0.08% | 13F |
| ING INVESTMENT MANAGEMENT CO | COM | 50,450 | 0.04% | 13F |
| SOCIETE GENERALE | COM | 48,329 | 0.04% | 13F |
| RODNEY SQUARE MANAGEMENT CORP | COMMON | 32,542 | 0.03% | 13F |
| MFC GLOBAL INVESTMENT MANAGEMENT (U.S.), LLC | COM | 32,028 | 0.03% | 13F |
| Charles Schwab Bank | COM | 29,000 | 0.02% | 13F |
| Manulife Asset Management (North America) Ltd | COM | 27,089 | 0.02% | 13F |
| Opus Trading Fund LLC | COM | 16,900 | 0.01% | 13F |
| KCG Holdings, Inc. | COM NEW | 14,238 | 0.01% | 13F |
| Nine Chapters Capital Management LLC | COM | 12,500 | 0.01% | 13F |
