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   <title>Form  S-8        Silence Therapeutics                 </title>
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   <title>Form  S-8        Silence Therapeutics                 </title>
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   <title>Form  S-8        Silence Therapeutics                 </title>
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   <title>Jefferies Reiterates Buy Rating on Silence Therapeutics (SLN): &quot;looks cheap at $175M+ EV&quot;</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Jefferies+Reiterates+Buy+Rating+on+Silence+Therapeutics+%28SLN%29%3A+%22looks+cheap+at+%24175M%2B+EV%22/26117243.html</link>
   <description>&lt;p&gt;Jefferies analyst Andrew Tsai reiterated a Buy rating and $25.00 price target on Silence Therapeutics (NASDAQ: SLN)&lt;/p&gt;&lt;p&gt;The analyst commented, &quot;In Aug 2026, divesiran's (TMPRSS6-targeting siRNA) important Phase II polycythemia vera (PV) data could lead to a +50-100% stock move ($1B+ oppty). For SLN's remaining siRNA pipeline: (1) In mid-26, competitor NVS/ IONS' pelacarsen (Lpa ASO) has Phase III CV outcomes data that could help Phase III-ready zerlasiran (Lpa siRNA) attract a BD partner ($1B+ call option). (2) In Q2:26, new preclinical data on cholesterol management (GPR146) and obesity (INHBE). SLN looks cheap at $175M+ EV despite having a mid-/late-stage pipeline</description>
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   <title>Form  10-K       Silence Therapeutics      For: Dec 31</title>
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   <title>Form  10-K       Silence Therapeutics      For: Dec 31</title>
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   <title>Form  10-K       Silence Therapeutics      For: Dec 31</title>
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   <title>Form  8-K        Silence Therapeutics      For: Mar 05</title>
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   <title>Form  8-K        Silence Therapeutics      For: Mar 05</title>
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   <title>Form  8-K        Silence Therapeutics      For: Mar 05</title>
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   <title>Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results</title>
   <link>http://www.streetinsider.com/Press+Releases/Silence+Therapeutics+Highlights+Recent+Business+Achievements+and+Reports+Fourth+Quarter+and+Full+Year+2025+Financial+Results/26115119.html</link>
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&lt;p class=&quot;bwalignc&quot;&gt;
&lt;i&gt;Topline results for Phase 2 SANRECO trial of divesiran, a first-in-class siRNA for polycythemia vera (PV), on-track for third quarter of 2026&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    LONDON--(BUSINESS WIRE)--
Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financial results for the fourth quarter and full year ended December 31, 2025, and provided an update on recent business achievements.

&lt;/p&gt;&lt;p&gt;
“The past year was focused on clinical execution, demonstrated by the expedited enrollment in the Phase 2 SANRECO trial of divesiran in PV which is on-track for topline results in third quarter of 2026,” said</description>
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   <pubDate>Thu, 05 Mar 2026 07:30:00 +0000</pubDate>
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   <title>Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results</title>
   <link>http://www.streetinsider.com/Press+Releases/Silence+Therapeutics+Highlights+Recent+Business+Achievements+and+Reports+Fourth+Quarter+and+Full+Year+2025+Financial+Results/26115119.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
&lt;i&gt;Topline results for Phase 2 SANRECO trial of divesiran, a first-in-class siRNA for polycythemia vera (PV), on-track for third quarter of 2026&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    LONDON--(BUSINESS WIRE)--
Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financial results for the fourth quarter and full year ended December 31, 2025, and provided an update on recent business achievements.

&lt;/p&gt;&lt;p&gt;
“The past year was focused on clinical execution, demonstrated by the expedited enrollment in the Phase 2 SANRECO trial of divesiran in PV which is on-track for topline results in third quarter of 2026,” said</description>
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   <pubDate>Thu, 05 Mar 2026 07:30:00 +0000</pubDate>
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   <title>Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results</title>
   <link>http://www.streetinsider.com/Business+Wire/Silence+Therapeutics+Highlights+Recent+Business+Achievements+and+Reports+Fourth+Quarter+and+Full+Year+2025+Financial+Results/26115119.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
&lt;i&gt;Topline results for Phase 2 SANRECO trial of divesiran, a first-in-class siRNA for polycythemia vera (PV), on-track for third quarter of 2026&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    LONDON--(BUSINESS WIRE)--
Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financial results for the fourth quarter and full year ended December 31, 2025, and provided an update on recent business achievements.

&lt;/p&gt;&lt;p&gt;
“The past year was focused on clinical execution, demonstrated by the expedited enrollment in the Phase 2 SANRECO trial of divesiran in PV which is on-track for topline results in third quarter of 2026,” said</description>
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   <pubDate>Thu, 05 Mar 2026 07:30:00 +0000</pubDate>
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   <title>Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results</title>
   <link>http://www.streetinsider.com/Business+Wire/Silence+Therapeutics+Highlights+Recent+Business+Achievements+and+Reports+Fourth+Quarter+and+Full+Year+2025+Financial+Results/26115119.html</link>
   <description>
&lt;p class=&quot;bwalignc&quot;&gt;
&lt;i&gt;Topline results for Phase 2 SANRECO trial of divesiran, a first-in-class siRNA for polycythemia vera (PV), on-track for third quarter of 2026&lt;/i&gt;

&lt;/p&gt;
&lt;p&gt;    LONDON--(BUSINESS WIRE)--
Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financial results for the fourth quarter and full year ended December 31, 2025, and provided an update on recent business achievements.

&lt;/p&gt;&lt;p&gt;
“The past year was focused on clinical execution, demonstrated by the expedited enrollment in the Phase 2 SANRECO trial of divesiran in PV which is on-track for topline results in third quarter of 2026,” said</description>
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   <pubDate>Thu, 05 Mar 2026 07:30:00 +0000</pubDate>
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   <title>William Blair Reiterates Outperform Rating on Silence Therapeutics (SLN)</title>
   <link>http://www.streetinsider.com/Analyst+Comments/William+Blair+Reiterates+Outperform+Rating+on+Silence+Therapeutics+%28SLN%29/26091296.html</link>
   <description>&lt;p&gt;William Blair analyst Myles Minter reiterated an Outperform rating on Silence Therapeutics (NASDAQ: SLN)&lt;/p&gt;&lt;p&gt;The analyst commented, &quot;We continue to view divesiran, a GalNAc-conjugated siRNA targeting TMPRSS6 for hepcidin upregulation, as underappreciated. The fully enrolled Phase II placebo-controlled SANRECO trial of divesiran is on track to report top-line data in the third quarter of 2026 with a presentation at ASH in December likely. With rusfertide’s positive Phase III VERIFY study we continue to believe that therapeutic approaches to boost hepcidin levels in PV are de-risked (see: Protagonist's Rusfertide Hits on Phase III Data; Positive Read-Through for Tmprss6-Targeting Asset Class). We continue</description>
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   <pubDate>Mon, 02 Mar 2026 15:06:20 +0000</pubDate>
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   <title>Form  4          Silence Therapeutics      For: Aug 03  Filed by: Griffiths Richard Ian</title>
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   <title>Form  4          Silence Therapeutics      For: Aug 03  Filed by: Griffiths Richard Ian</title>
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   <title>Form  4          Silence Therapeutics      For: Aug 03  Filed by: Griffiths Richard Ian</title>
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   <title>Form  SCHEDULE 13G/A  Silence Therapeutics                   Filed by: Lombard Odier Asset Management (USA) Corp</title>
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   <title>Form  8-K        Southland Holdings, Inc.  For: Feb 04</title>
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