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   <title>Rhythm Pharmaceuticals Announces New Data Presentations at the European Society for Paediatric Endocrinology Meeting</title>
   <link>http://www.streetinsider.com/Press+Releases/Rhythm+Pharmaceuticals+Announces+New+Data+Presentations+at+the+European+Society+for+Paediatric+Endocrinology+Meeting/27045297.html</link>
   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Real-world data showed reductions in BMI with up to 18 months of setmelanotide therapy in 30 paediatric patients with acquired hypothalamic obesity (HO) in France –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Phase 3 analyses demonstrated improvements across multiple cardiometabolic risk indices with setmelanotide in acquired HO --&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;BOSTON, Sept.  10, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced Rhythm and its collaborators will present three posters and three oral presentations relating to the company’s work in rare melanocortin-4</description>
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   <pubDate>Thu, 10 Sep 2026 08:00:00 -0400</pubDate>
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   <title>Rhythm Pharmaceuticals Announces New Data Presentations at the European Society for Paediatric Endocrinology Meeting</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Rhythm+Pharmaceuticals+Announces+New+Data+Presentations+at+the+European+Society+for+Paediatric+Endocrinology+Meeting/27045297.html</link>
   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Real-world data showed reductions in BMI with up to 18 months of setmelanotide therapy in 30 paediatric patients with acquired hypothalamic obesity (HO) in France –&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Phase 3 analyses demonstrated improvements across multiple cardiometabolic risk indices with setmelanotide in acquired HO --&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;BOSTON, Sept.  10, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced Rhythm and its collaborators will present three posters and three oral presentations relating to the company’s work in rare melanocortin-4</description>
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   <pubDate>Thu, 10 Sep 2026 08:00:00 -0400</pubDate>
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   <title>Deutsche Bank Starts Rhythm Pharmaceuticals (RYTM) at Hold</title>
   <link>http://www.streetinsider.com/New+Coverage/Deutsche+Bank+Starts+Rhythm+Pharmaceuticals+%28RYTM%29+at+Hold/26990588.html</link>
   <description>&lt;p&gt;Deutsche Bank analyst David Hoang initiates coverage on Rhythm Pharmaceuticals (NASDAQ: RYTM) with a Hold rating and a price target of $120.00.&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on Rhythm Pharmaceuticals &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=RYTM&quot;&gt;click here&lt;/a&gt;. For more ratings news on Rhythm Pharmaceuticals &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=RYTM&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of Rhythm Pharmaceuticals closed at $111.87 yesterday.&lt;/p&gt;</description>
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   <pubDate>Thu, 27 Aug 2026 16:36:27 -0400</pubDate>
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   <title>Rhythm gets Japan approval for obesity drug Imcivree</title>
   <link>http://www.streetinsider.com/Corporate+News/Rhythm+gets+Japan+approval+for+obesity+drug+Imcivree/26964475.html</link>
   <description>&lt;p&gt;Rhythm Pharmaceuticals (Nasdaq: RYTM) announced that Japan's Ministry of Health, Labour and Welfare has granted marketing authorization to Imcivree (setmelanotide) for the treatment of acquired hypothalamic obesity, according to a company statement.&lt;/p&gt;&lt;p&gt;Imcivree, a melanocortin-4 receptor agonist, is described by Rhythm as the first therapy approved in Japan for this condition. The company estimates between 5,000 and 8,000 people in Japan are living with acquired hypothalamic obesity, a rare disease characterized by accelerated and sustained weight gain caused by injury to the hypothalamus.&lt;/p&gt;&lt;p&gt;Rhythm expects to commercially launch Imcivree in Japan before the end of 2026, pending final pricing determination.&lt;/p&gt;&lt;p&gt;The approval is</description>
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   <pubDate>Mon, 24 Aug 2026 08:03:23 -0400</pubDate>
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   <title>Rhythm gets Japan approval for obesity drug Imcivree</title>
   <link>http://www.streetinsider.com/FDA/Rhythm+gets+Japan+approval+for+obesity+drug+Imcivree/26964475.html</link>
   <description>&lt;p&gt;Rhythm Pharmaceuticals (Nasdaq: RYTM) announced that Japan's Ministry of Health, Labour and Welfare has granted marketing authorization to Imcivree (setmelanotide) for the treatment of acquired hypothalamic obesity, according to a company statement.&lt;/p&gt;&lt;p&gt;Imcivree, a melanocortin-4 receptor agonist, is described by Rhythm as the first therapy approved in Japan for this condition. The company estimates between 5,000 and 8,000 people in Japan are living with acquired hypothalamic obesity, a rare disease characterized by accelerated and sustained weight gain caused by injury to the hypothalamus.&lt;/p&gt;&lt;p&gt;Rhythm expects to commercially launch Imcivree in Japan before the end of 2026, pending final pricing determination.&lt;/p&gt;&lt;p&gt;The approval is</description>
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   <pubDate>Mon, 24 Aug 2026 08:03:23 -0400</pubDate>
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   <title>Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan</title>
   <link>http://www.streetinsider.com/Press+Releases/Rhythm+Pharmaceuticals+Announces+MHLW+Approval+of+IMCIVREE%C2%AE+%28setmelanotide%29+for+Patients+with+Acquired+Hypothalamic+Obesity+%28HO%29+in+Japan/26964365.html</link>
   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Approximately 5,000 to 8,000 patients estimated to be living with acquired HO in Japan -- &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Commercial launch in Japan expected by end of 2026, pending final pricing determination -- &lt;/em&gt;&lt;/p&gt;  &lt;p&gt;BOSTON, Aug.  24, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced that Japan’s Ministry of Health, Labour and Welfare (MHLW) has granted marketing authorization to IMCIVREE&lt;sup&gt;®&lt;/sup&gt; (setmelanotide) to treat patients living with acquired hypothalamic obesity (HO).&lt;/p&gt;  &lt;p&gt;IMCIVREE, a melanocortin-4 receptor (MC4R) agonist which received</description>
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   <pubDate>Mon, 24 Aug 2026 08:00:00 -0400</pubDate>
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   <title>Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Rhythm+Pharmaceuticals+Announces+MHLW+Approval+of+IMCIVREE%C2%AE+%28setmelanotide%29+for+Patients+with+Acquired+Hypothalamic+Obesity+%28HO%29+in+Japan/26964365.html</link>
   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Approximately 5,000 to 8,000 patients estimated to be living with acquired HO in Japan -- &lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;-- Commercial launch in Japan expected by end of 2026, pending final pricing determination -- &lt;/em&gt;&lt;/p&gt;  &lt;p&gt;BOSTON, Aug.  24, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced that Japan’s Ministry of Health, Labour and Welfare (MHLW) has granted marketing authorization to IMCIVREE&lt;sup&gt;®&lt;/sup&gt; (setmelanotide) to treat patients living with acquired hypothalamic obesity (HO).&lt;/p&gt;  &lt;p&gt;IMCIVREE, a melanocortin-4 receptor (MC4R) agonist which received</description>
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   <pubDate>Mon, 24 Aug 2026 08:00:00 -0400</pubDate>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 17  Filed by: Joshi Manher</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++RHYTHM+PHARMACEUTICALS%2C+++For%3A+Aug+17++Filed+by%3A+Joshi+Manher/26945615.html</link>
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   <pubDate>Tue, 18 Aug 2026 17:35:00 -0400</pubDate>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 17  Filed by: Joshi Manher</title>
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   <title>Form  3          RHYTHM PHARMACEUTICALS,   For: Aug 17  Filed by: Joshi Manher</title>
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   <title>Form  3          RHYTHM PHARMACEUTICALS,   For: Aug 17  Filed by: Joshi Manher</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++3++++++++++RHYTHM+PHARMACEUTICALS%2C+++For%3A+Aug+17++Filed+by%3A+Joshi+Manher/26945452.html</link>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Shulman Joseph</title>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Shulman Joseph</title>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Garfield Alastair</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++RHYTHM+PHARMACEUTICALS%2C+++For%3A+Aug+13++Filed+by%3A+Garfield+Alastair/26939104.html</link>
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   <pubDate>Mon, 17 Aug 2026 17:58:00 -0400</pubDate>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Garfield Alastair</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++RHYTHM+PHARMACEUTICALS%2C+++For%3A+Aug+13++Filed+by%3A+Garfield+Alastair/26939104.html</link>
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   <title>Rhythm Pharmaceuticals names Manher Joshi as chief medical officer</title>
   <link>http://www.streetinsider.com/Management+Changes/Rhythm+Pharmaceuticals+names+Manher+Joshi+as+chief+medical+officer/26935081.html</link>
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&lt;p&gt;Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM) has appointed Manher &quot;AJ&quot; Joshi, M.D., as Chief Medical Officer, effective Aug. 17, according to a company statement.&lt;/p&gt;

&lt;p&gt;Dr. Joshi joins Rhythm from Soleno Therapeutics, where he served as Chief Development Officer. His prior roles include Chief Medical Officer at Neurona Therapeutics and Executive Vice President, Chief Medical Officer and Head of Clinical Development at Atara Biotherapeutics. Earlier in his career, he held positions at Allergan Medical, Hunt Bioventures, Synageva BioPharma Corp., Genzyme and HealthBanks.&lt;/p&gt;

&lt;p&gt;Dr. Joshi holds a B.A. and M.D. from Boston University and Boston University School of Medicine and completed a residency in Internal</description>
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   <pubDate>Mon, 17 Aug 2026 08:00:53 -0400</pubDate>
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   <title>Rhythm Pharmaceuticals Announces Appointment of Manher (AJ) Joshi as Chief Medical Officer</title>
   <link>http://www.streetinsider.com/Press+Releases/Rhythm+Pharmaceuticals+Announces+Appointment+of+Manher+%28AJ%29+Joshi+as+Chief+Medical+Officer/26935002.html</link>
   <description>&lt;p&gt;BOSTON, Aug.  17, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced the appointment of Manher “AJ” Joshi, M.D., as Chief Medical Officer, effective August 17.&lt;/p&gt;  &lt;p&gt;“We are excited to welcome AJ to Rhythm as we enter a new stage of growth and continue to expand our global impact for patients living with rare neuroendocrine diseases,” said David Meeker, M.D., Rhythm Chairman, President and Chief Executive Officer. “AJ brings more than two decades of leadership and experience from</description>
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   <pubDate>Mon, 17 Aug 2026 08:00:00 -0400</pubDate>
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   <title>Rhythm Pharmaceuticals Announces Appointment of Manher (AJ) Joshi as Chief Medical Officer</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Rhythm+Pharmaceuticals+Announces+Appointment+of+Manher+%28AJ%29+Joshi+as+Chief+Medical+Officer/26935002.html</link>
   <description>&lt;p&gt;BOSTON, Aug.  17, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced the appointment of Manher “AJ” Joshi, M.D., as Chief Medical Officer, effective August 17.&lt;/p&gt;  &lt;p&gt;“We are excited to welcome AJ to Rhythm as we enter a new stage of growth and continue to expand our global impact for patients living with rare neuroendocrine diseases,” said David Meeker, M.D., Rhythm Chairman, President and Chief Executive Officer. “AJ brings more than two decades of leadership and experience from</description>
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   <pubDate>Mon, 17 Aug 2026 08:00:00 -0400</pubDate>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Lee Jennifer Kayden</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++RHYTHM+PHARMACEUTICALS%2C+++For%3A+Aug+13++Filed+by%3A+Lee+Jennifer+Kayden/26933189.html</link>
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   <pubDate>Fri, 14 Aug 2026 19:05:00 -0400</pubDate>
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   <title>Form  4          RHYTHM PHARMACEUTICALS,   For: Aug 13  Filed by: Lee Jennifer Kayden</title>
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