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   <title>Form  DEFA14A    Transcode Therapeutics,              </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++DEFA14A++++Transcode+Therapeutics%2C++++++++++++++/26101343.html</link>
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   <pubDate>Tue, 03 Mar 2026 16:09:00 -0500</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">O.50607779</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>Form  DEFA14A    Transcode Therapeutics,              </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++DEFA14A++++Transcode+Therapeutics%2C++++++++++++++/26101343.html</link>
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   <pubDate>Tue, 03 Mar 2026 16:09:00 -0500</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>Form  8-K        Transcode Therapeutics,   For: Mar 02</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Transcode+Therapeutics%2C+++For%3A+Mar+02/26101272.html</link>
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   <pubDate>Tue, 03 Mar 2026 16:08:00 -0500</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>Form  8-K        Transcode Therapeutics,   For: Mar 02</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Transcode+Therapeutics%2C+++For%3A+Mar+02/26101272.html</link>
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   <pubDate>Tue, 03 Mar 2026 16:08:00 -0500</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>TransCode licenses cancer immunotherapy platform in stock deal</title>
   <link>http://www.streetinsider.com/Corporate+News/TransCode+licenses+cancer+immunotherapy+platform+in+stock+deal/26096921.html</link>
   <description>&lt;p&gt;TransCode Therapeutics Inc. (NASDAQ: RNAZ) announced it entered into an exclusive, worldwide, royalty-free license agreement with Unleash Immuno Oncolytics Inc. to develop three drug candidates: UIO-524, UIO-525 and UIO-526.&lt;/p&gt;&lt;p&gt;Under the agreement, Unleash will receive 1,136,364 shares of a new series of non-voting convertible preferred stock from TransCode, convertible into an equal number of common stock shares. The preferred stock represents 6.8% of TransCode's common stock on a fully diluted basis assuming conversion of all outstanding preferred stock.&lt;/p&gt;&lt;p&gt;The lead candidate UIO-524 is designed as an oncolytic adenovirus engineered to replicate within malignant cells and cancer-associated stroma. The virus delivers cytokines CD40-L,</description>
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   <pubDate>Tue, 03 Mar 2026 08:03:22 -0500</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>TransCode licenses cancer immunotherapy platform in stock deal</title>
   <link>http://www.streetinsider.com/Hot+Corp.+News/TransCode+licenses+cancer+immunotherapy+platform+in+stock+deal/26096921.html</link>
   <description>&lt;p&gt;TransCode Therapeutics Inc. (NASDAQ: RNAZ) announced it entered into an exclusive, worldwide, royalty-free license agreement with Unleash Immuno Oncolytics Inc. to develop three drug candidates: UIO-524, UIO-525 and UIO-526.&lt;/p&gt;&lt;p&gt;Under the agreement, Unleash will receive 1,136,364 shares of a new series of non-voting convertible preferred stock from TransCode, convertible into an equal number of common stock shares. The preferred stock represents 6.8% of TransCode's common stock on a fully diluted basis assuming conversion of all outstanding preferred stock.&lt;/p&gt;&lt;p&gt;The lead candidate UIO-524 is designed as an oncolytic adenovirus engineered to replicate within malignant cells and cancer-associated stroma. The virus delivers cytokines CD40-L,</description>
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   <pubDate>Tue, 03 Mar 2026 08:03:22 -0500</pubDate>
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   <title>TransCode Secures Exclusive, Worldwide, Fully Paid-Up Royalty-Free License to Develop and Commercialize a Next-Generation Oncolytic Immunotherapy Platform in an All-Stock Transaction Underscoring the </title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Secures+Exclusive%2C+Worldwide%2C+Fully+Paid-Up+Royalty-Free+License+to+Develop+and+Commercialize+a+Next-Generation+Oncolytic+Immunotherapy+Platform+in+an+All-Stock+Transaction+Underscoring+the+/26096901.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;i&gt;TransCode adds a unique adenovirus technology platform to its early-stage pipeline that has the potential to address a difficult to treat disease such as muscle-invasive bladder cancer.&lt;/i&gt;&lt;/li&gt;&lt;/ul&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;March 3, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;b&gt;&lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ)&lt;/b&gt;, a clinical stage company pioneering immuno-oncology and RNA for the treatment of high risk and advanced cancer, today announced that it has entered into an exclusive, worldwide, fully paid-up royalty-free license agreement with &lt;span&gt;Unleash Immuno Oncolytics, Inc.&lt;/span&gt; (&quot;Unleash&quot;). TransCode obtained the rights to develop three Unleash drug candidates, UIO-524, UIO-525 and UIO-526, which</description>
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   <pubDate>Tue, 03 Mar 2026 08:01:00 -0500</pubDate>
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   <title>TransCode Secures Exclusive, Worldwide, Fully Paid-Up Royalty-Free License to Develop and Commercialize a Next-Generation Oncolytic Immunotherapy Platform in an All-Stock Transaction Underscoring the </title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Secures+Exclusive%2C+Worldwide%2C+Fully+Paid-Up+Royalty-Free+License+to+Develop+and+Commercialize+a+Next-Generation+Oncolytic+Immunotherapy+Platform+in+an+All-Stock+Transaction+Underscoring+the+/26096901.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;i&gt;TransCode adds a unique adenovirus technology platform to its early-stage pipeline that has the potential to address a difficult to treat disease such as muscle-invasive bladder cancer.&lt;/i&gt;&lt;/li&gt;&lt;/ul&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;March 3, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;b&gt;&lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ)&lt;/b&gt;, a clinical stage company pioneering immuno-oncology and RNA for the treatment of high risk and advanced cancer, today announced that it has entered into an exclusive, worldwide, fully paid-up royalty-free license agreement with &lt;span&gt;Unleash Immuno Oncolytics, Inc.&lt;/span&gt; (&quot;Unleash&quot;). TransCode obtained the rights to develop three Unleash drug candidates, UIO-524, UIO-525 and UIO-526, which</description>
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   <pubDate>Tue, 03 Mar 2026 08:01:00 -0500</pubDate>
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   <title>TransCode Secures Exclusive, Worldwide, Fully Paid-Up Royalty-Free License to Develop and Commercialize a Next-Generation Oncolytic Immunotherapy Platform in an All-Stock Transaction Underscoring the </title>
   <link>http://www.streetinsider.com/PRNewswire/TransCode+Secures+Exclusive%2C+Worldwide%2C+Fully+Paid-Up+Royalty-Free+License+to+Develop+and+Commercialize+a+Next-Generation+Oncolytic+Immunotherapy+Platform+in+an+All-Stock+Transaction+Underscoring+the+/26096901.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;i&gt;TransCode adds a unique adenovirus technology platform to its early-stage pipeline that has the potential to address a difficult to treat disease such as muscle-invasive bladder cancer.&lt;/i&gt;&lt;/li&gt;&lt;/ul&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;March 3, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;b&gt;&lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ)&lt;/b&gt;, a clinical stage company pioneering immuno-oncology and RNA for the treatment of high risk and advanced cancer, today announced that it has entered into an exclusive, worldwide, fully paid-up royalty-free license agreement with &lt;span&gt;Unleash Immuno Oncolytics, Inc.&lt;/span&gt; (&quot;Unleash&quot;). TransCode obtained the rights to develop three Unleash drug candidates, UIO-524, UIO-525 and UIO-526, which</description>
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   <pubDate>Tue, 03 Mar 2026 08:01:00 -0500</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">O.50607779</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>TransCode Secures Exclusive, Worldwide, Fully Paid-Up Royalty-Free License to Develop and Commercialize a Next-Generation Oncolytic Immunotherapy Platform in an All-Stock Transaction Underscoring the </title>
   <link>http://www.streetinsider.com/PRNewswire/TransCode+Secures+Exclusive%2C+Worldwide%2C+Fully+Paid-Up+Royalty-Free+License+to+Develop+and+Commercialize+a+Next-Generation+Oncolytic+Immunotherapy+Platform+in+an+All-Stock+Transaction+Underscoring+the+/26096901.html</link>
   <description>
&lt;div class=&quot;xn-content&quot;&gt;
&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;i&gt;TransCode adds a unique adenovirus technology platform to its early-stage pipeline that has the potential to address a difficult to treat disease such as muscle-invasive bladder cancer.&lt;/i&gt;&lt;/li&gt;&lt;/ul&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;March 3, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;b&gt;&lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ)&lt;/b&gt;, a clinical stage company pioneering immuno-oncology and RNA for the treatment of high risk and advanced cancer, today announced that it has entered into an exclusive, worldwide, fully paid-up royalty-free license agreement with &lt;span&gt;Unleash Immuno Oncolytics, Inc.&lt;/span&gt; (&quot;Unleash&quot;). TransCode obtained the rights to develop three Unleash drug candidates, UIO-524, UIO-525 and UIO-526, which</description>
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   <pubDate>Tue, 03 Mar 2026 08:01:00 -0500</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>Form  8-K        Transcode Therapeutics,   For: Feb 23</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Transcode+Therapeutics%2C+++For%3A+Feb+23/26039710.html</link>
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   <pubDate>Mon, 23 Feb 2026 08:11:00 -0500</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">O.50607779</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>Form  8-K        Transcode Therapeutics,   For: Feb 23</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Transcode+Therapeutics%2C+++For%3A+Feb+23/26039710.html</link>
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   <pubDate>Mon, 23 Feb 2026 08:11:00 -0500</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">O.50607779</category>
   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Therapeutics+Announces+Publication+of+Preclinical+Testing+of+RIG-I+Immunotherapeutic+Candidate+Supporting+Further+Development/26039621.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <pubDate>Mon, 23 Feb 2026 08:01:00 -0500</pubDate>
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   	   	<category domain="http://rss.financialcontent.com/stocksymbol">RNAZ</category>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Therapeutics+Announces+Publication+of+Preclinical+Testing+of+RIG-I+Immunotherapeutic+Candidate+Supporting+Further+Development/26039621.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <pubDate>Mon, 23 Feb 2026 08:01:00 -0500</pubDate>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Therapeutics+Announces+Publication+of+Preclinical+Testing+of+RIG-I+Immunotherapeutic+Candidate+Supporting+Further+Development/26039621.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
   <link>http://www.streetinsider.com/Press+Releases/TransCode+Therapeutics+Announces+Publication+of+Preclinical+Testing+of+RIG-I+Immunotherapeutic+Candidate+Supporting+Further+Development/26039621.html</link>
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&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
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&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
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&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
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&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ma.boston&quot; idsrc=&quot;xmltag.org&quot; &gt;BOSTON&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Feb. 23, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RNAZ&quot; idsrc=&quot;xmltag.org&quot; &gt;TransCode Therapeutics, Inc.&lt;/span&gt; (NASDAQ: RNAZ), a clinical stage company pioneering immuno-oncology and RNA therapeutics for the treatment of high risk and advanced cancers, today announced the publication of a manuscript titled &lt;i&gt;&lt;span&gt;Template-Directed RIG-I Agonist Assembly&lt;/span&gt; for Image-guided Targeted Cancer Immunotherapy&lt;/i&gt; in the journal &lt;i&gt;Molecular Imaging and Biology&lt;/i&gt;. The paper, published &lt;chron&gt;February 19, 2026&lt;/chron&gt;, reports on a novel tumor-selective immunotherapy approach that activates innate immune signaling specifically within cancer cells while enabling non-invasive imaging of drug delivery. The study was carried out in collaboration with Dr. Anna Moore, Professor,</description>
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   <title>TransCode Therapeutics Announces Publication of Preclinical Testing of RIG-I Immunotherapeutic Candidate Supporting Further Development</title>
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   <title>TransCode submits IND amendment for phase 2a colorectal cancer trial</title>
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&lt;p&gt;TransCode Therapeutics Inc. (NASDAQ: RNAZ) and Quantum Leap Healthcare Collaborative submitted an Investigational New Drug application amendment to the U.S. Food and Drug Administration for a phase 2a clinical trial with TTX-MC138, according to a company statement.&lt;/p&gt;

&lt;p&gt;The study will be conducted within Quantum Leap's PRE-I-SPY program and represents the program's first expansion into colorectal cancer. The phase 2a dose-expansion trial will enroll up to 45 patients with colorectal cancer who have completed standard curative-intent therapy and have positive markers for circulating tumor DNA.&lt;/p&gt;

&lt;p&gt;Dr. Paula Pohlmann of MD Anderson Cancer Center will serve as principal investigator. The trial is planned to</description>
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   <title>TransCode submits IND amendment for phase 2a colorectal cancer trial</title>
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&lt;p&gt;TransCode Therapeutics Inc. (NASDAQ: RNAZ) and Quantum Leap Healthcare Collaborative submitted an Investigational New Drug application amendment to the U.S. Food and Drug Administration for a phase 2a clinical trial with TTX-MC138, according to a company statement.&lt;/p&gt;

&lt;p&gt;The study will be conducted within Quantum Leap's PRE-I-SPY program and represents the program's first expansion into colorectal cancer. The phase 2a dose-expansion trial will enroll up to 45 patients with colorectal cancer who have completed standard curative-intent therapy and have positive markers for circulating tumor DNA.&lt;/p&gt;

&lt;p&gt;Dr. Paula Pohlmann of MD Anderson Cancer Center will serve as principal investigator. The trial is planned to</description>
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&lt;p&gt;TransCode Therapeutics Inc. (NASDAQ: RNAZ) and Quantum Leap Healthcare Collaborative submitted an Investigational New Drug application amendment to the U.S. Food and Drug Administration for a phase 2a clinical trial with TTX-MC138, according to a company statement.&lt;/p&gt;

&lt;p&gt;The study will be conducted within Quantum Leap's PRE-I-SPY program and represents the program's first expansion into colorectal cancer. The phase 2a dose-expansion trial will enroll up to 45 patients with colorectal cancer who have completed standard curative-intent therapy and have positive markers for circulating tumor DNA.&lt;/p&gt;

&lt;p&gt;Dr. Paula Pohlmann of MD Anderson Cancer Center will serve as principal investigator. The trial is planned to</description>
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