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   <title>Form  4          Rapport Therapeutics,     For: Oct 21  Filed by: Ceesay Abraham</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+21++Filed+by%3A+Ceesay+Abraham/27228206.html</link>
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   <pubDate>Fri, 23 Oct 2026 16:30:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 23  Filed by: Sanchez Ramiro</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+23++Filed+by%3A+Sanchez+Ramiro/27227795.html</link>
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   <pubDate>Fri, 23 Oct 2026 16:01:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 22  Filed by: PAUL STEVEN M</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+22++Filed+by%3A+PAUL+STEVEN+M/27223337.html</link>
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   <pubDate>Thu, 22 Oct 2026 16:57:00 -0400</pubDate>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 22  Filed by: Young Wendy B.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+22++Filed+by%3A+Young+Wendy+B./27223340.html</link>
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   <pubDate>Thu, 22 Oct 2026 16:57:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 22  Filed by: Silva Paul M</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+22++Filed+by%3A+Silva+Paul+M/27223342.html</link>
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   <pubDate>Thu, 22 Oct 2026 16:57:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 22  Filed by: MARAGANORE JOHN</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+22++Filed+by%3A+MARAGANORE+JOHN/27223333.html</link>
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   <pubDate>Thu, 22 Oct 2026 16:56:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Form  4          Rapport Therapeutics,     For: Oct 21  Filed by: Ignelzi Troy A.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++Rapport+Therapeutics%2C+++++For%3A+Oct+21++Filed+by%3A+Ignelzi+Troy+A./27217405.html</link>
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   <pubDate>Wed, 21 Oct 2026 17:47:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $82 at Jones Trading</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2482+at+Jones+Trading/27212599.html</link>
   <description>(Updated - October 21, 2026 6:17 AM EDT)

&lt;p&gt;Jones Trading analyst Justin Walsh raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $82.00 (from $50.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;With RAP-219 now demonstrating that it could actually become a &quot;pipeline-in-a-product&quot; with clinical trial wins in both FOS and BPM, we have conviction in the long-term potential of RAPP and believe the stock is attractively priced at current levels. We reiterate our Buy rating and increase our 12-month price target to $82 from $50.&quot;&lt;/p&gt;</description>
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   <pubDate>Wed, 21 Oct 2026 06:17:17 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $82 at Jones Trading</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2482+at+Jones+Trading/27212599.html</link>
   <description>(Updated - October 21, 2026 6:17 AM EDT)

&lt;p&gt;Jones Trading analyst Justin Walsh raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $82.00 (from $50.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;With RAP-219 now demonstrating that it could actually become a &quot;pipeline-in-a-product&quot; with clinical trial wins in both FOS and BPM, we have conviction in the long-term potential of RAPP and believe the stock is attractively priced at current levels. We reiterate our Buy rating and increase our 12-month price target to $82 from $50.&quot;&lt;/p&gt;</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2482+at+Jones+Trading/27212599.html</guid>
   <pubDate>Wed, 21 Oct 2026 06:17:17 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $82 at Jones Trading</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2482+at+Jones+Trading/27212600.html</link>
   <description>&lt;p&gt;Jones Trading analyst Justin Walsh raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $82.00 (from $50.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;With RAP-219 now demonstrating that it could actually become a &quot;pipeline-in-a-product&quot; with clinical trial wins in both FOS and BPM, we have conviction in the long-term potential of RAPP and believe the stock is attractively priced at current levels. We reiterate our Buy rating and increase our 12-month price target to $82 from $50.&quot;&lt;/p&gt;</description>
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   <pubDate>Wed, 21 Oct 2026 06:17:01 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $82 at Jones Trading</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2482+at+Jones+Trading/27212600.html</link>
   <description>&lt;p&gt;Jones Trading analyst Justin Walsh raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $82.00 (from $50.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;With RAP-219 now demonstrating that it could actually become a &quot;pipeline-in-a-product&quot; with clinical trial wins in both FOS and BPM, we have conviction in the long-term potential of RAPP and believe the stock is attractively priced at current levels. We reiterate our Buy rating and increase our 12-month price target to $82 from $50.&quot;&lt;/p&gt;</description>
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   <pubDate>Wed, 21 Oct 2026 06:17:01 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Lowered to $50 at Wells Fargo</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Lowered+to+%2450+at+Wells+Fargo/27212157.html</link>
   <description>&lt;p&gt;Wells Fargo analyst Ben Burnett lowered the price target on Rapport Therapeutics (NASDAQ: RAPP) to $50.00 (from $51.00) while maintaining a Overweight rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Our take: we think we've learned that RAP-219 is a non-sedating drug that carries a risk of agitation and possibly anxiety. We think agitation, at these rates, is unlikely to be a major commercial barrier in FOS. We are lowering our PoS in FOS slightly, now 60%, given the potential for this to drive discontinuations which were notable in the FOS Ph2. Bipolar seems riskier to us, as we think efficacy is marginal, and we're</description>
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   <pubDate>Wed, 21 Oct 2026 05:24:31 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Lowered to $50 at Wells Fargo</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Lowered+to+%2450+at+Wells+Fargo/27212157.html</link>
   <description>&lt;p&gt;Wells Fargo analyst Ben Burnett lowered the price target on Rapport Therapeutics (NASDAQ: RAPP) to $50.00 (from $51.00) while maintaining a Overweight rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Our take: we think we've learned that RAP-219 is a non-sedating drug that carries a risk of agitation and possibly anxiety. We think agitation, at these rates, is unlikely to be a major commercial barrier in FOS. We are lowering our PoS in FOS slightly, now 60%, given the potential for this to drive discontinuations which were notable in the FOS Ph2. Bipolar seems riskier to us, as we think efficacy is marginal, and we're</description>
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   <pubDate>Wed, 21 Oct 2026 05:24:31 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $70 at Guggenheim</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2470+at+Guggenheim/27209691.html</link>
   <description>(Updated - October 20, 2026 2:00 PM EDT)

&lt;p&gt;Guggenheim analyst Delma Caiati raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $70.00 (from $65.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;RAPP's Ph2 trial in bipolar mania (n=253) hit both primary (YMRS −3.1 pts placebo-adjusted, p=0.045) and secondary (CGI-BP −0.4, p=0.024) endpoints. While the delta came in below the 4-pt powering assumption, the 15.4-pt absolute YMRS reduction is consistent with recent mania trials, with the placebo-adjusted effect compressed by a placebo response (12.3 pts) at the upper end of recent ranges. Separation widened weekly, all 11 YMRS items numerically favored</description>
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   <pubDate>Tue, 20 Oct 2026 14:00:02 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $70 at Guggenheim</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2470+at+Guggenheim/27209691.html</link>
   <description>(Updated - October 20, 2026 2:00 PM EDT)

&lt;p&gt;Guggenheim analyst Delma Caiati raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $70.00 (from $65.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;RAPP's Ph2 trial in bipolar mania (n=253) hit both primary (YMRS −3.1 pts placebo-adjusted, p=0.045) and secondary (CGI-BP −0.4, p=0.024) endpoints. While the delta came in below the 4-pt powering assumption, the 15.4-pt absolute YMRS reduction is consistent with recent mania trials, with the placebo-adjusted effect compressed by a placebo response (12.3 pts) at the upper end of recent ranges. Separation widened weekly, all 11 YMRS items numerically favored</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2470+at+Guggenheim/27209691.html</guid>
   <pubDate>Tue, 20 Oct 2026 14:00:02 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $86 at Raymond James</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2486+at+Raymond+James/27209221.html</link>
   <description>&lt;p&gt;Raymond James analyst Tiago Fauth raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $86.00 (from $75.00) while maintaining a Strong Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Thoughts on the stock. With RAPP trading roughly flat following its positive bipolar readout, we suspect the market is primarily focused on the 3.1-point placebo-adjusted YMRS benefit falling short of the ~4-point benchmark investors had hoped for. In a more constructive market, we believe these results would have been better received. Recall, our deep dive highlighted substantial downside support from RAP-219's potentially best-in-class FOS franchise, with bipolar representing significant incremental upside. Yet, RAPP is</description>
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   <pubDate>Tue, 20 Oct 2026 12:15:44 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics (RAPP) PT Raised to $86 at Raymond James</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2486+at+Raymond+James/27209221.html</link>
   <description>&lt;p&gt;Raymond James analyst Tiago Fauth raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $86.00 (from $75.00) while maintaining a Strong Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Thoughts on the stock. With RAPP trading roughly flat following its positive bipolar readout, we suspect the market is primarily focused on the 3.1-point placebo-adjusted YMRS benefit falling short of the ~4-point benchmark investors had hoped for. In a more constructive market, we believe these results would have been better received. Recall, our deep dive highlighted substantial downside support from RAP-219's potentially best-in-class FOS franchise, with bipolar representing significant incremental upside. Yet, RAPP is</description>
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   <pubDate>Tue, 20 Oct 2026 12:15:44 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Wolfe Defending Rapport Therapeutics (RAPP) </title>
   <link>http://www.streetinsider.com/Trader+Talk/Wolfe+Defending+Rapport+Therapeutics+%28RAPP%29+/27208563.html</link>
   <description>&lt;p&gt;Wolfe Defending Rapport Therapeutics (NASDAQ: RAPP)&lt;/p&gt;&lt;ul&gt;&lt;li&gt;Shares traded as high as $52 premarket, currently trading $30 handle.&lt;/li&gt;&lt;li&gt;Wolfe: &quot;Great buying opportunity following positive biopolar mania&quot;.&lt;/li&gt;&lt;li&gt;RAPP shares up 6% on the day currently.&lt;/li&gt;&lt;li&gt;YTD RAPP is up 0.64%.&lt;br /&gt; &lt;/li&gt;&lt;/ul&gt;</description>
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   <pubDate>Tue, 20 Oct 2026 10:30:12 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Truist Securities Reiterates Buy Rating on Rapport Therapeutics (RAPP)</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Truist+Securities+Reiterates+Buy+Rating+on+Rapport+Therapeutics+%28RAPP%29/27208495.html</link>
   <description>&lt;p&gt;Truist Securities analyst Danielle Brill reiterated a Buy rating and $56.00 price target on Rapport Therapeutics (NASDAQ: RAPP).&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Bottom Line: We entered the readout with low expectations but are pleasantly surprised that RAP-219 established proof-of-concept in bipolar mania. Consistent efficacy and planned Ph 3 enhancements support cautious optimism, while the continued clean safety profile provides an encouraging read-through to the lead FOS program. Reiterate Buy.&quot;&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on Rapport Therapeutics &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=RAPP&quot;&gt;click here&lt;/a&gt;. For more ratings news on Rapport Therapeutics &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=RAPP&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of Rapport Therapeutics closed at $28.60 yesterday.&lt;/p&gt;</description>
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   <pubDate>Tue, 20 Oct 2026 10:18:17 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Truist Securities Reiterates Buy Rating on Rapport Therapeutics (RAPP)</title>
   <link>http://www.streetinsider.com/Hot+Comments/Truist+Securities+Reiterates+Buy+Rating+on+Rapport+Therapeutics+%28RAPP%29/27208495.html</link>
   <description>&lt;p&gt;Truist Securities analyst Danielle Brill reiterated a Buy rating and $56.00 price target on Rapport Therapeutics (NASDAQ: RAPP).&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Bottom Line: We entered the readout with low expectations but are pleasantly surprised that RAP-219 established proof-of-concept in bipolar mania. Consistent efficacy and planned Ph 3 enhancements support cautious optimism, while the continued clean safety profile provides an encouraging read-through to the lead FOS program. Reiterate Buy.&quot;&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on Rapport Therapeutics &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=RAPP&quot;&gt;click here&lt;/a&gt;. For more ratings news on Rapport Therapeutics &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=RAPP&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of Rapport Therapeutics closed at $28.60 yesterday.&lt;/p&gt;</description>
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   <pubDate>Tue, 20 Oct 2026 10:18:17 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>TD Cowen on Rapport Therapeutics (RAPP): 'Meaningful upside remains'</title>
   <link>http://www.streetinsider.com/Hot+Comments/TD+Cowen+on+Rapport+Therapeutics+%28RAPP%29%3A+%27Meaningful+upside+remains%27/27208280.html</link>
   <description>&lt;p&gt;TD Cowen analyst Joseph Thome reiterated a Buy rating on Rapport Therapeutics (NASDAQ: RAPP).&lt;/p&gt;&lt;p&gt;The analyst comments &quot;RAPP announced that the Phase II trial of RAP-219 in bipolar mania hit the YMRS primary endpoint with a 3.1 point placebo-adjusted improvement at week 3 (15.4 point improvement in RAP-219 vs. 12.3 in placebo; p=0.045). RAP-219 produced benefit on all YMRS items with nominal significance on irritability (p=0.013), thought content (p=0.049), disruptive aggressive behavior (p=0.047), and sexual interest (p=0.026). Irritability and disruptive aggressive behavior are considered among the most disabling BPM symptoms.&lt;/p&gt;&lt;p&gt;The key secondary endpoint was also met with a 0.4-point LS mean</description>
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   <pubDate>Tue, 20 Oct 2026 09:55:02 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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  <item>
   <title>TD Cowen on Rapport Therapeutics (RAPP): 'Meaningful upside remains'</title>
   <link>http://www.streetinsider.com/Analyst+Comments/TD+Cowen+on+Rapport+Therapeutics+%28RAPP%29%3A+%27Meaningful+upside+remains%27/27208280.html</link>
   <description>&lt;p&gt;TD Cowen analyst Joseph Thome reiterated a Buy rating on Rapport Therapeutics (NASDAQ: RAPP).&lt;/p&gt;&lt;p&gt;The analyst comments &quot;RAPP announced that the Phase II trial of RAP-219 in bipolar mania hit the YMRS primary endpoint with a 3.1 point placebo-adjusted improvement at week 3 (15.4 point improvement in RAP-219 vs. 12.3 in placebo; p=0.045). RAP-219 produced benefit on all YMRS items with nominal significance on irritability (p=0.013), thought content (p=0.049), disruptive aggressive behavior (p=0.047), and sexual interest (p=0.026). Irritability and disruptive aggressive behavior are considered among the most disabling BPM symptoms.&lt;/p&gt;&lt;p&gt;The key secondary endpoint was also met with a 0.4-point LS mean</description>
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   <pubDate>Tue, 20 Oct 2026 09:55:02 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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  <item>
   <title>Rapport Therapeutics (RAPP) PT Raised to $89 at BTIG</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2489+at+BTIG/27208189.html</link>
   <description>&lt;p&gt;BTIG analyst Kambiz Yazdi raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $89.00 (from $75.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;RAP-219 cleared every major hurdle in this pivotal proofof-concept mania readout, meeting primary and secondary endpoints with statistically significant improvement in manic symptoms and consistent benefit across all YMRS measures. RAP-219 was well tolerated, with no severe TEAEs or SAEs on treatment, providing compelling clinical validation of TARPγ8-selective AMPAR modulation as a viable new mechanism in mania. Importantly, efficacy was achieved with low rates of somnolence and dizziness and no akathisia, avoiding much of the classic</description>
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   <pubDate>Tue, 20 Oct 2026 09:38:42 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
   	  </item>
  <item>
   <title>Rapport Therapeutics (RAPP) PT Raised to $89 at BTIG</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2489+at+BTIG/27208189.html</link>
   <description>&lt;p&gt;BTIG analyst Kambiz Yazdi raised the price target on Rapport Therapeutics (NASDAQ: RAPP) to $89.00 (from $75.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;RAP-219 cleared every major hurdle in this pivotal proofof-concept mania readout, meeting primary and secondary endpoints with statistically significant improvement in manic symptoms and consistent benefit across all YMRS measures. RAP-219 was well tolerated, with no severe TEAEs or SAEs on treatment, providing compelling clinical validation of TARPγ8-selective AMPAR modulation as a viable new mechanism in mania. Importantly, efficacy was achieved with low rates of somnolence and dizziness and no akathisia, avoiding much of the classic</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+Comments/Rapport+Therapeutics+%28RAPP%29+PT+Raised+to+%2489+at+BTIG/27208189.html</guid>
   <pubDate>Tue, 20 Oct 2026 09:38:42 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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   <title>Rapport Therapeutics soars over 50% as bipolar mania drug meets trial goals</title>
   <link>http://www.streetinsider.com/Investing/Rapport+Therapeutics+soars+over+50%25+as+bipolar+mania+drug+meets+trial+goals/27206213.html</link>
   <description>&lt;p&gt;Investing.com -- Rapport Therapeutics shares rocketed more than 50% in premarket trading Tuesday after the company reported positive results from a mid-stage trial of its bipolar mania treatment RAP-219.&lt;/p&gt;
&lt;p&gt;The company said RAP-219 met its primary and secondary endpoints in a Phase 2 trial of 253 adults with bipolar I disorder experiencing acute manic episodes. The treatment achieved a statistically significant 3.1-point placebo-adjusted improvement in the Young Mania Rating Scale (YMRS) total score at week 3. &lt;/p&gt;
&lt;p&gt;Patients who took RAP-219 had a 15.4-point mean reduction in YMRS total score from baseline at week 3, compared to a 12.3-point reduction with placebo. The</description>
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   <pubDate>Tue, 20 Oct 2026 06:40:06 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RAPP</category>
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