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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
   <description>
&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
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   <description>
&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
   <description>
&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
   <description>
&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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   <title>ORYZON Announces U.S. Patent Grant for Vafidemstat in Borderline Personality Disorder (BPD)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/ORYZON+Announces+U.S.+Patent+Grant+for+Vafidemstat+in+Borderline+Personality+Disorder+%28BPD%29/26744524.html</link>
   <description>
&lt;ul type=&quot;disc&quot;&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Granted claims cover the use of vafidemstat for treating non-aggressive symptoms of BPD&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;U.S. patent to expire in March 2043, including 1,095 days of Patent Term Adjustment&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;margin-top:6pt; text-align:left;&quot;&gt;&lt;strong&gt;Notice of allowance also received in a corresponding Canadian patent application&lt;/strong&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  08, 2026  (GLOBE NEWSWIRE) -- Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company and global leader in epigenetics, today announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 12,673,044, entitled “Methods of treating borderline personality disorder”. The</description>
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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

&lt;p&gt;The subscription price represents a 14.15% discount to the five-day volume-weighted average price of €3.1449 and a 12.68% discount to the June 30 closing price of €3.092. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK.&lt;/p&gt;

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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

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   <title>Oryzon raises €12M in share offering, secures €25M COFIDES commitment</title>
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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

&lt;p&gt;The subscription price represents a 14.15% discount to the five-day volume-weighted average price of €3.1449 and a 12.68% discount to the June 30 closing price of €3.092. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK.&lt;/p&gt;

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   <title>Oryzon raises €12M in share offering, secures €25M COFIDES commitment</title>
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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

&lt;p&gt;The subscription price represents a 14.15% discount to the five-day volume-weighted average price of €3.1449 and a 12.68% discount to the June 30 closing price of €3.092. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK.&lt;/p&gt;

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   <title>Oryzon raises €12M in share offering, secures €25M COFIDES commitment</title>
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&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

&lt;p&gt;The subscription price represents a 14.15% discount to the five-day volume-weighted average price of €3.1449 and a 12.68% discount to the June 30 closing price of €3.092. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK.&lt;/p&gt;

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   <title>Oryzon raises €12M in share offering, secures €25M COFIDES commitment</title>
   <link>http://www.streetinsider.com/Corporate+News/Oryzon+raises+%E2%82%AC12M+in+share+offering%2C+secures+%E2%82%AC25M+COFIDES+commitment/26717908.html</link>
   <description>

&lt;p&gt;Oryzon Genomics, S.A. (ISIN: ES0167733015, ORY) completed a €12 million gross capital increase on July 1, 2026, through the issuance of 4,444,445 new ordinary shares priced at €2.70 per share.&lt;/p&gt;

&lt;p&gt;The subscription price represents a 14.15% discount to the five-day volume-weighted average price of €3.1449 and a 12.68% discount to the June 30 closing price of €3.092. The offering was structured as a capital increase without the issuance of warrants. Singular Bank acted as placement agent in Spain, and All-Invest acted as placement agent in the EU and the UK.&lt;/p&gt;

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   <title>ORYZON Raises €12 Million and Signs a Financing Agreement with COFIDES to Strengthen its Balance Sheet and Accelerate its Clinical Programs</title>
   <link>http://www.streetinsider.com/Press+Releases/ORYZON+Raises+%E2%82%AC12+Million+and+Signs+a+Financing+Agreement+with+COFIDES+to+Strengthen+its+Balance+Sheet+and+Accelerate+its+Clinical+Programs/26717905.html</link>
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&lt;ul&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;&lt;strong&gt;Issued 4,444,445 new ordinary shares &lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;&lt;strong&gt;Priced at €2.70 per share, representing a 14.15% discount on the five-day VWAP and a 12.68% discount to the June 30 closing price&lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;&lt;strong&gt;The transaction has been structured as a capital increase without the issuance of warrants &lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;&lt;strong&gt;Proceeds will be used to advance the Company&amp;apos;s clinical development programs and support other corporate initiatives &lt;/strong&gt;&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;&lt;strong&gt;The Social Impact Fund, managed by COFIDES, has committed to invest €25 million in future capital increases to support Oryzon&amp;apos;s mental health programs, subject to certain conditions&lt;/strong&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;MADRID and CAMBRIDGE, Mass., July  01, 2026 </description>
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   <pubDate>Wed, 01 Jul 2026 09:08:00 -0400</pubDate>
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