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   <title>Truist Securities Reiterates Buy Rating on Cytokinetics (CYTK)</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Truist+Securities+Reiterates+Buy+Rating+on+Cytokinetics+%28CYTK%29/27007602.html</link>
   <description>&lt;p&gt;Truist Securities analyst Srikripa Devarakonda reiterated a Buy rating and $112.00 price target on Cytokinetics (NASDAQ: CYTK).&lt;/p&gt;&lt;p&gt;The analyst comments &quot;We reiterate our Buy for CYTK following detailed ACACIA analyses at ESC this past weekend. Despite ACACIA's imbalance in heart failure (4.7% vs. 1.2% pbo), we see a sizable and under-appreciated opportunity with Myqorzo in HCM (we model $5.8B in WW peak rev; 2036E). KOL checks highlight HF as a known side effect of CMIs, ACACIA had no afi-related deaths, improved HF rates with real-world-like use (FOREST-HCM). We believe Myqorzo will likely become the first approved therapy for nHCM (possibly with</description>
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   <pubDate>Tue, 01 Sep 2026 03:56:19 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics aficamten shows cardiac benefits in two HCM trial analyses</title>
   <link>http://www.streetinsider.com/Corporate+News/Cytokinetics+aficamten+shows+cardiac+benefits+in+two+HCM+trial+analyses/27000250.html</link>
   <description>&lt;p&gt;Cytokinetics, Incorporated (Nasdaq: CYTK) announced additional results from two Phase 3 clinical trials of aficamten at the European Society of Cardiology Congress 2026 in Munich, Germany, with findings simultaneously published in &lt;em&gt;Circulation&lt;/em&gt; and the &lt;em&gt;Journal of the American College of Cardiology: Heart Failure&lt;/em&gt;.&lt;/p&gt;&lt;p&gt;A pre-specified exploratory analysis of the ACACIA-HCM trial, which studied aficamten in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM), showed improvements in cardiac structure and diastolic function beyond the previously reported gains in exercise capacity and symptom burden. At 36 weeks and at end of treatment, aficamten significantly improved measures of diastolic function including peak E velocity and</description>
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   <pubDate>Mon, 31 Aug 2026 06:05:19 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics aficamten shows cardiac benefits in two HCM trial analyses</title>
   <link>http://www.streetinsider.com/FDA/Cytokinetics+aficamten+shows+cardiac+benefits+in+two+HCM+trial+analyses/27000250.html</link>
   <description>&lt;p&gt;Cytokinetics, Incorporated (Nasdaq: CYTK) announced additional results from two Phase 3 clinical trials of aficamten at the European Society of Cardiology Congress 2026 in Munich, Germany, with findings simultaneously published in &lt;em&gt;Circulation&lt;/em&gt; and the &lt;em&gt;Journal of the American College of Cardiology: Heart Failure&lt;/em&gt;.&lt;/p&gt;&lt;p&gt;A pre-specified exploratory analysis of the ACACIA-HCM trial, which studied aficamten in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM), showed improvements in cardiac structure and diastolic function beyond the previously reported gains in exercise capacity and symptom burden. At 36 weeks and at end of treatment, aficamten significantly improved measures of diastolic function including peak E velocity and</description>
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   <pubDate>Mon, 31 Aug 2026 06:05:19 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics Announces Additional Results from ACACIA-HCM and MAPLE-HCM Presented in Late Breaking Clinical Trial Session at the European Society of Cardiology (ESC) Congress 2026</title>
   <link>http://www.streetinsider.com/Press+Releases/Cytokinetics+Announces+Additional+Results+from+ACACIA-HCM+and+MAPLE-HCM+Presented+in+Late+Breaking+Clinical+Trial+Session+at+the+European+Society+of+Cardiology+%28ESC%29+Congress+2026/26999552.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Additional Results from ACACIA-HCM Demonstrate Improvements in &lt;/em&gt;&lt;em&gt;Cardiac Structure and Diastolic Function in Patients with Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New Analysis of MAPLE-HCM Finds Aficamten Outperformed Metoprolol Across Pre-Trial Treatment Groups in Patients with Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  29, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that additional results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;) and MAPLE-HCM (&lt;strong&gt;&lt;em&gt;M&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;etoprolol&lt;/em&gt; vs &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; in &lt;strong&gt;P&lt;/strong&gt;atients with &lt;strong&gt;L&lt;/strong&gt;VOT Obstruction on &lt;strong&gt;E&lt;/strong&gt;xercise Capacity in &lt;strong&gt;HCM&lt;/strong&gt;) were presented in a Late Breaking Clinical Session at the European</description>
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   <pubDate>Sat, 29 Aug 2026 10:30:00 -0400</pubDate>
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   <title>Cytokinetics Announces Additional Results from ACACIA-HCM and MAPLE-HCM Presented in Late Breaking Clinical Trial Session at the European Society of Cardiology (ESC) Congress 2026</title>
   <link>http://www.streetinsider.com/Press+Releases/Cytokinetics+Announces+Additional+Results+from+ACACIA-HCM+and+MAPLE-HCM+Presented+in+Late+Breaking+Clinical+Trial+Session+at+the+European+Society+of+Cardiology+%28ESC%29+Congress+2026/26999552.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Additional Results from ACACIA-HCM Demonstrate Improvements in &lt;/em&gt;&lt;em&gt;Cardiac Structure and Diastolic Function in Patients with Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New Analysis of MAPLE-HCM Finds Aficamten Outperformed Metoprolol Across Pre-Trial Treatment Groups in Patients with Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  29, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that additional results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;) and MAPLE-HCM (&lt;strong&gt;&lt;em&gt;M&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;etoprolol&lt;/em&gt; vs &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; in &lt;strong&gt;P&lt;/strong&gt;atients with &lt;strong&gt;L&lt;/strong&gt;VOT Obstruction on &lt;strong&gt;E&lt;/strong&gt;xercise Capacity in &lt;strong&gt;HCM&lt;/strong&gt;) were presented in a Late Breaking Clinical Session at the European</description>
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   <pubDate>Sat, 29 Aug 2026 10:30:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics Announces Additional Results from ACACIA-HCM and MAPLE-HCM Presented in Late Breaking Clinical Trial Session at the European Society of Cardiology (ESC) Congress 2026</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Cytokinetics+Announces+Additional+Results+from+ACACIA-HCM+and+MAPLE-HCM+Presented+in+Late+Breaking+Clinical+Trial+Session+at+the+European+Society+of+Cardiology+%28ESC%29+Congress+2026/26999552.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Additional Results from ACACIA-HCM Demonstrate Improvements in &lt;/em&gt;&lt;em&gt;Cardiac Structure and Diastolic Function in Patients with Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New Analysis of MAPLE-HCM Finds Aficamten Outperformed Metoprolol Across Pre-Trial Treatment Groups in Patients with Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  29, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that additional results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;) and MAPLE-HCM (&lt;strong&gt;&lt;em&gt;M&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;etoprolol&lt;/em&gt; vs &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; in &lt;strong&gt;P&lt;/strong&gt;atients with &lt;strong&gt;L&lt;/strong&gt;VOT Obstruction on &lt;strong&gt;E&lt;/strong&gt;xercise Capacity in &lt;strong&gt;HCM&lt;/strong&gt;) were presented in a Late Breaking Clinical Session at the European</description>
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   <pubDate>Sat, 29 Aug 2026 10:30:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics Announces Additional Results from ACACIA-HCM and MAPLE-HCM Presented in Late Breaking Clinical Trial Session at the European Society of Cardiology (ESC) Congress 2026</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Cytokinetics+Announces+Additional+Results+from+ACACIA-HCM+and+MAPLE-HCM+Presented+in+Late+Breaking+Clinical+Trial+Session+at+the+European+Society+of+Cardiology+%28ESC%29+Congress+2026/26999552.html</link>
   <description>
&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Additional Results from ACACIA-HCM Demonstrate Improvements in &lt;/em&gt;&lt;em&gt;Cardiac Structure and Diastolic Function in Patients with Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New Analysis of MAPLE-HCM Finds Aficamten Outperformed Metoprolol Across Pre-Trial Treatment Groups in Patients with Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  29, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that additional results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;) and MAPLE-HCM (&lt;strong&gt;&lt;em&gt;M&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;etoprolol&lt;/em&gt; vs &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; in &lt;strong&gt;P&lt;/strong&gt;atients with &lt;strong&gt;L&lt;/strong&gt;VOT Obstruction on &lt;strong&gt;E&lt;/strong&gt;xercise Capacity in &lt;strong&gt;HCM&lt;/strong&gt;) were presented in a Late Breaking Clinical Session at the European</description>
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   <pubDate>Sat, 29 Aug 2026 10:30:00 -0400</pubDate>
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   <title>Form  8-K        CYTOKINETICS INC          For: Aug 28</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++CYTOKINETICS+INC++++++++++For%3A+Aug+28/26993767.html</link>
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   <pubDate>Fri, 28 Aug 2026 09:22:00 -0400</pubDate>
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   <title>Form  8-K        CYTOKINETICS INC          For: Aug 28</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++CYTOKINETICS+INC++++++++++For%3A+Aug+28/26993767.html</link>
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   <pubDate>Fri, 28 Aug 2026 09:22:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics aficamten meets dual endpoints in non-obstructive HCM trial</title>
   <link>http://www.streetinsider.com/Corporate+News/Cytokinetics+aficamten+meets+dual+endpoints+in+non-obstructive+HCM+trial/26992225.html</link>
   <description>&lt;p&gt;Cytokinetics, Incorporated (Nasdaq: CYTK) announced that its Phase 3 ACACIA-HCM clinical trial of aficamten in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM) met both dual primary endpoints, according to results presented at the European Society of Cardiology Congress 2026 in Munich, Germany, and simultaneously published in &lt;em&gt;The New England Journal of Medicine&lt;/em&gt;.&lt;/p&gt;&lt;p&gt;The trial of 517 participants showed statistically significant improvements from baseline to Week 36 compared to placebo in both the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) and maximal exercise performance (pVO2). The KCCQ-CSS improvement for aficamten versus placebo showed a least square mean difference of 3.0 points</description>
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   <pubDate>Fri, 28 Aug 2026 05:51:41 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics aficamten meets dual endpoints in non-obstructive HCM trial</title>
   <link>http://www.streetinsider.com/FDA/Cytokinetics+aficamten+meets+dual+endpoints+in+non-obstructive+HCM+trial/26992225.html</link>
   <description>&lt;p&gt;Cytokinetics, Incorporated (Nasdaq: CYTK) announced that its Phase 3 ACACIA-HCM clinical trial of aficamten in patients with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM) met both dual primary endpoints, according to results presented at the European Society of Cardiology Congress 2026 in Munich, Germany, and simultaneously published in &lt;em&gt;The New England Journal of Medicine&lt;/em&gt;.&lt;/p&gt;&lt;p&gt;The trial of 517 participants showed statistically significant improvements from baseline to Week 36 compared to placebo in both the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) and maximal exercise performance (pVO2). The KCCQ-CSS improvement for aficamten versus placebo showed a least square mean difference of 3.0 points</description>
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   <pubDate>Fri, 28 Aug 2026 05:51:41 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">CYTK</category>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
   <link>http://www.streetinsider.com/Press+Releases/Cytokinetics+Announces+Positive+Results+from+ACACIA-HCM+Presented+in+Hot+Line+Session+at+the+European+Society+of+Cardiology+%28ESC%29+Congress+2026+and+Published+in+The+New+England+Journal+of+Medicine/26992211.html</link>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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   <title>Cytokinetics Announces Positive Results from ACACIA-HCM Presented in Hot Line Session at the European Society of Cardiology (ESC) Congress 2026 and Published in The New England Journal of Medicine</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;ACACIA-HCM is the First Phase 3 Clinical Trial to Successfully Demonstrate Statistically Significant Improvements Across Both Patient-Reported and Physician-Assessed Endpoints in Non-Obstructive HCM&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Supplemental New Drug Application to be Submitted to FDA in Fourth Quarter&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Company to Host Investor Event and Webcast Today at 2:00 PM Central European Summer Time (8:00 AM Eastern Time)&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;SOUTH SAN FRANCISCO, Calif., Aug.  28, 2026  (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced the primary results from ACACIA-HCM (&lt;strong&gt;A&lt;/strong&gt;ssessment &lt;strong&gt;C&lt;/strong&gt;omparing &lt;strong&gt;&lt;em&gt;A&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;ficamten&lt;/em&gt; to Placebo on &lt;strong&gt;C&lt;/strong&gt;ardiac Endpoints &lt;strong&gt;I&lt;/strong&gt;n &lt;strong&gt;A&lt;/strong&gt;dults with Non-Obstructive &lt;strong&gt;HCM&lt;/strong&gt;), the pivotal Phase</description>
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