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   <title>FDA clears Corbus Pharma to begin CRB-701 cancer study</title>
   <link>http://www.streetinsider.com/Corporate+News/FDA+clears+Corbus+Pharma+to+begin+CRB-701+cancer+study/26822819.html</link>
   <description>&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) announced that the U.S. Food and Drug Administration has cleared the start of its registrational study, known as TEMPO-1, of CRB-701 in second-line oropharyngeal squamous cell carcinoma (OPSCC). The company expects to begin enrollment in September 2026.&lt;/p&gt;&lt;p&gt;TEMPO-1 is a randomized controlled study enrolling 250 patients, designed to evaluate the efficacy and safety of CRB-701 compared with investigator's choice of capecitabine, cetuximab, or docetaxel. The study's primary endpoint is objective response rate, intended to support a potential accelerated approval, while overall survival is intended to support potential conversion to full approval.&lt;/p&gt;&lt;p&gt;The FDA's clearance was supported</description>
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   <title>FDA clears Corbus Pharma to begin CRB-701 cancer study</title>
   <link>http://www.streetinsider.com/FDA/FDA+clears+Corbus+Pharma+to+begin+CRB-701+cancer+study/26822819.html</link>
   <description>&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) announced that the U.S. Food and Drug Administration has cleared the start of its registrational study, known as TEMPO-1, of CRB-701 in second-line oropharyngeal squamous cell carcinoma (OPSCC). The company expects to begin enrollment in September 2026.&lt;/p&gt;&lt;p&gt;TEMPO-1 is a randomized controlled study enrolling 250 patients, designed to evaluate the efficacy and safety of CRB-701 compared with investigator's choice of capecitabine, cetuximab, or docetaxel. The study's primary endpoint is objective response rate, intended to support a potential accelerated approval, while overall survival is intended to support potential conversion to full approval.&lt;/p&gt;&lt;p&gt;The FDA's clearance was supported</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Corbus+Pharmaceuticals+Announces+FDA+Clearance+to+Initiate+TEMPO-1+Registrational+Study+of+CRB-701+in+Patients+with+2L+Oropharyngeal+Cancer/26822770.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;em&gt;Company expects to initiate enrollment in TEMPO-1 in September 2026&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;li style=&quot;margin-bottom:1pt;&quot;&gt;&lt;em&gt;OPSCC is estimated to represent 1 in 2 head and neck cancer patients in the 2L setting in the U.S. with approximately 14,000 patients eligible annually for treatment &lt;/em&gt;&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;    &lt;p align=&quot;justify&quot;&gt;NORWOOD, Mass., July  28, 2026  (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”) a clinical-stage company focusing on developing new therapies in oncology and obesity, today announced that the U.S. Food and Drug Administration (FDA) has cleared the start of the Company’s registrational study (“TEMPO-1”) of CRB-701, a next-generation</description>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
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   <title>Corbus Pharmaceuticals Announces FDA Clearance to Initiate TEMPO-1 Registrational Study of CRB-701 in Patients with 2L Oropharyngeal Cancer</title>
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   <title>Form  8-K        Corbus Pharmaceuticals    For: Jul 02</title>
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&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has appointed Leonardo Viana Nicacio, M.D., as Chief Medical Officer, according to a company statement.&lt;/p&gt;

&lt;p&gt;Dr. Nicacio brings more than 20 years of pharmaceutical industry experience, most recently serving as Chief Medical Officer at Protara Therapeutics. Before that, he was Senior Vice President, Head of Clinical Development and Global Medical Affairs at Stemline Therapeutics, a subsidiary of the Menarini Group.&lt;/p&gt;

&lt;p&gt;From 2017 to 2023, Dr. Nicacio held roles of increasing responsibility at Seagen, which was acquired by Pfizer in December 2023, most recently as Vice President of Clinical Development. In that role, he worked on programs</description>
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&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has appointed Leonardo Viana Nicacio, M.D., as Chief Medical Officer, according to a company statement.&lt;/p&gt;

&lt;p&gt;Dr. Nicacio brings more than 20 years of pharmaceutical industry experience, most recently serving as Chief Medical Officer at Protara Therapeutics. Before that, he was Senior Vice President, Head of Clinical Development and Global Medical Affairs at Stemline Therapeutics, a subsidiary of the Menarini Group.&lt;/p&gt;

&lt;p&gt;From 2017 to 2023, Dr. Nicacio held roles of increasing responsibility at Seagen, which was acquired by Pfizer in December 2023, most recently as Vice President of Clinical Development. In that role, he worked on programs</description>
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&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has appointed Leonardo Viana Nicacio, M.D., as Chief Medical Officer, according to a company statement.&lt;/p&gt;

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&lt;p&gt;From 2017 to 2023, Dr. Nicacio held roles of increasing responsibility at Seagen, which was acquired by Pfizer in December 2023, most recently as Vice President of Clinical Development. In that role, he worked on programs</description>
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&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has appointed Leonardo Viana Nicacio, M.D., as Chief Medical Officer, according to a company statement.&lt;/p&gt;

&lt;p&gt;Dr. Nicacio brings more than 20 years of pharmaceutical industry experience, most recently serving as Chief Medical Officer at Protara Therapeutics. Before that, he was Senior Vice President, Head of Clinical Development and Global Medical Affairs at Stemline Therapeutics, a subsidiary of the Menarini Group.&lt;/p&gt;

&lt;p&gt;From 2017 to 2023, Dr. Nicacio held roles of increasing responsibility at Seagen, which was acquired by Pfizer in December 2023, most recently as Vice President of Clinical Development. In that role, he worked on programs</description>
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&lt;p&gt;Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has appointed Leonardo Viana Nicacio, M.D., as Chief Medical Officer, according to a company statement.&lt;/p&gt;

&lt;p&gt;Dr. Nicacio brings more than 20 years of pharmaceutical industry experience, most recently serving as Chief Medical Officer at Protara Therapeutics. Before that, he was Senior Vice President, Head of Clinical Development and Global Medical Affairs at Stemline Therapeutics, a subsidiary of the Menarini Group.&lt;/p&gt;

&lt;p&gt;From 2017 to 2023, Dr. Nicacio held roles of increasing responsibility at Seagen, which was acquired by Pfizer in December 2023, most recently as Vice President of Clinical Development. In that role, he worked on programs</description>
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