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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO</title>
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&lt;p align=&quot;justify&quot; style=&quot;padding-left:0pt;&quot;&gt;CALGARY, Alberta, June  15, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to provide a corporate update and discussion of the strategic path for our gout and other programs.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The Company’s current focus, following the recent financing and growing investor interest, is solidly aimed at restructuring our corporate and issuer status, re-initiating our drug development programs, and preparing regulatory filings associated with our lead</description>
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   <title>XORTX Announces Election to Voluntary Delist from the TSX Venture Exchange</title>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, June  12, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that the Company has elected to voluntarily delist its common shares from the TSX Venture Exchange (“TSXV”). The Company will provide additional information on timing for the completion of the delisting of its common shares in a separate press release.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;This decision was taken following a comprehensive evaluation, the Company determined that maintaining a</description>
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   <title>XORTX Announces Election to Voluntary Delist from the TSX Venture Exchange</title>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, June  12, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that the Company has elected to voluntarily delist its common shares from the TSX Venture Exchange (“TSXV”). The Company will provide additional information on timing for the completion of the delisting of its common shares in a separate press release.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;This decision was taken following a comprehensive evaluation, the Company determined that maintaining a</description>
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   <pubDate>Fri, 12 Jun 2026 17:00:00 -0400</pubDate>
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   <title>XORTX Announces Election to Voluntary Delist from the TSX Venture Exchange</title>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, June  12, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that the Company has elected to voluntarily delist its common shares from the TSX Venture Exchange (“TSXV”). The Company will provide additional information on timing for the completion of the delisting of its common shares in a separate press release.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;This decision was taken following a comprehensive evaluation, the Company determined that maintaining a</description>
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   <title>XORTX Announces Election to Voluntary Delist from the TSX Venture Exchange</title>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, June  12, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that the Company has elected to voluntarily delist its common shares from the TSX Venture Exchange (“TSXV”). The Company will provide additional information on timing for the completion of the delisting of its common shares in a separate press release.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;This decision was taken following a comprehensive evaluation, the Company determined that maintaining a</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, June  12, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that the Company has elected to voluntarily delist its common shares from the TSX Venture Exchange (“TSXV”). The Company will provide additional information on timing for the completion of the delisting of its common shares in a separate press release.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;This decision was taken following a comprehensive evaluation, the Company determined that maintaining a</description>
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