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Feb 12, 2019 10:00AM Form SC 13G/A MEDICINES CO /DE Filed by: WELLINGTON MANAGEMENT GROUP LLP

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Feb 14, 2018 05:54PM Form SC 13G/A MEDICINES CO /DE Filed by: Partner Fund Management, L.P.

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May 1, 2017 04:06PM Form SC 13G MEDICINES CO /DE Filed by: Partner Fund Management, L.P.

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Jan 12, 2017 05:16PM Form SC 13G/A MEDICINES CO /DE Filed by: BlackRock Inc.

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Feb 10, 2016 02:41PM Form SC 13G/A MEDICINES CO /DE Filed by: VANGUARD GROUP INC

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Feb 17, 2015 05:08PM Form SC 13G/A MEDICINES CO /DE Filed by: PointState Capital LP

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Jan 9, 2015 04:45PM Form SC 13G/A MEDICINES CO /DE Filed by: BlackRock Inc.

Oct 20, 2014 09:32AM

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