Onymos and Vanta Diagnostics Collaborate to Scale Intelligent Lab Intake

SAN FRANCISCO, Sept. 2, 2026 /PRNewswire/ -- Onymos, a leader in intelligent document processing for precision medicine, and Vanta Diagnostics, a leading provider of molecular laboratory services, today announced the results of their collaboration, demonstrating how using AI-assisted intake increased operational efficiency by up to 72%, expanded laboratory capacity by more than 300 samples per day, and reduced accessioning errors by 40%.

Increasingly complex tests, persistent staffing shortages, and evolving payer requirements have made laboratory intake a significant operational bottleneck and source of friction. Errors introduced during this process often cascade into testing delays, billing issues, compliance risks, and preventable rework.

To address these challenges, Onymos and Vanta deployed the Onymos DocKnow intelligent intake platform within Vanta's accessioning workflow, transforming incoming forms and documents into validated, structured data before being shared with downstream systems.

Following implementation, Vanta realized dramatic gains across multiple metrics, including:

• Increasing operational efficiency by up to 72% and reducing requisition processing times to as little as one minute.
• Expanding laboratory capacity by more than 300 additional samples per day (approximately 6,500 samples per month) while using fewer laboratory personnel.
• Reducing accessioning errors by 40%, improving data quality, and minimizing downstream rework.

As we were initially evaluating Onymos DocKnow, we saw an opportunity to improve far more than the speed of document processing," said Mary Katherine DiFilippo, Director of Specimen Analytics at Vanta Diagnostics. "We recognized that by improving the quality of information and how our staff actually processes that information, we could create a much bigger impact."

"Our mission is to provide rapid results to patients using the most advanced diagnostics," added Dan Nodes, Chief Operating Officer of Vanta Diagnostics. "Achieving that requires continuous innovation not only in the tests we perform, but in the operational systems that support them. As we continue to grow, investing in intelligent intake helps ensure our operations can scale alongside our science."

Rather than simply digitizing documents, DocKnow interprets laboratory requisitions and supporting clinical documentation, validates information across multiple sources, and produces enriched outputs that integrate directly with the systems that laboratories already use.

Shiva Nathan, Founder and CEO of Onymos, believes the collaboration proves that "Measurable ROI with AI, not AI for AI's sake, will define the next generation of precision medicine. In just one quarter, our work with Vanta Diagnostics showed that intelligent intake can not only help laboratories scale, but also unlock improvements in quality, compliance, and turnaround time that were once considered difficult to achieve all at once. Together, we are proving that intake can be a source of competitive advantage."

Tony Mancuso, Director of Business Development at Onymos, said the results also highlight a broader business reality. "The financial health of a laboratory depends on the quality of the information entering it. Organizations that view intelligent intake as a strategic investment in data quality are better positioned to reduce preventable denials and ultimately drive more revenue."

Onymos and Vanta Diagnostics are demonstrating a more practical path for AI in the laboratory by moving beyond experimentation and prioritizing measurable outcomes. As other laboratories and healthcare organizations look to maximize the return on technology investments, intelligent intake represents one of the clearest opportunities to turn AI into measurable business value.

About Onymos   
Onymos is transforming manual workflows in healthcare and life sciences. Its DocKnow platform captures, validates, and enriches data from complex documents, enabling organizations to improve data quality at scale, streamline their operations, and drive measurable ROI. To learn more, visit: www.onymos.com. 

About Vanta Diagnostics
Vanta Diagnostics is a national CLIA and CAP-certified laboratory with a dedicated team that provides a comprehensive range of medical diagnostic testing services across 45 states. The company is headquartered in South Carolina with additional laboratories in Pennsylvania and Florida. For more information, please visit vantadiagnostics.com.

Media Contact
Jamie Goodnight
Onymos   
[email protected] 

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SOURCE Onymos